K. P. Kim

Assessing Long-Term Stored Tissues for Multi-Omics Data Quality and Proteogenomics Suitability

This study evaluates the quality and suitability of long-term stored tissues for multi-omics analyses, showing that while transcriptomic data show some changes, core gene expression and proteomic measurements remain reliable.

Unbiased phosphoproteomics analysis unveils modulation of insulin signaling by extramitotic CDK1 kinase activity in human myotubes

The paper uses phosphoproteomics to show that CDK1 activity modulates insulin signaling and glucose uptake in human myotubes, with group-specific phosphorylation changes observed.

ECPAS/Ecm29-Mediated 26S Proteasome Disassembly Is an Adaptive Response to Glucose Starvation

This study shows that ECPAS-mediated 26S proteasome disassembly into 20S and 19S subcomplexes occurs during glucose starvation, enhancing proteolysis and cell survival.

P176S polymorphism in Maspin rewires electrostatic interaction that alters Maspin functionality

This study shows that the P176S polymorphism in Maspin alters electrostatic interactions, affecting its function and binding properties in cancer.

Synthetic glabridin derivatives mitigate steatohepatitis in a diet-induced biopsy-confirmed non-alcoholic steatosis hepatitis mouse model through paraoxonase-2

This study shows synthetic glabridin derivatives reduce NASH symptoms in mice by activating autophagy and antioxidant defenses through targeting paraoxonase-2.