T. Matsuda

Ras Activation by Hydrostatic Pressure is Enhanced by GAP and GEF in vitro

This study investigates how hydrostatic pressure activates Ras in vitro and shows that GAP and GEF domains enhance this activation.

Selective plane activation structured illumination microscopy

This study improves structured illumination microscopy by using selective plane illumination and photoswitchable proteins to eliminate out-of-focus background, enabling high-resolution imaging of volumetric samples.

Genomic surveillance of antimicrobial-resistant Escherichia coli in fecal sludge and sewage in Uganda

This study uses genomic surveillance of E. coli from Ugandan fecal sludge and sewage to track antimicrobial resistance patterns and identify key resistance determinants.

Identification of key virus--prokaryote infection pairs that contribute to viral shunt in a freshwater lake

The paper identifies key virus-prokaryote infection pairs that drive viral shunt in a freshwater lake by analyzing metagenomic data from surface and deep layers over a year.

Porcine placenta extract upregulates ceramide synthase 3 expression via the PPARδ/ILK/Akt/mTOR/STAT3 pathway

This study identifies the PPARδ/ILK/Akt/mTOR/STAT3 pathway as the mechanism by which porcine placenta extract upregulates ceramide synthase 3 expression in HaCaT cells.

Emergence of rare carbapenemases (FRI, GES-5, IMI, SFC, and SFH-1) in Enterobacterales isolated from surface waters in Japan

This study identifies rare carbapenemases in environmental Enterobacterales from Japan, revealing their genetic contexts and plasmid locations.

Prediction of antigen-responding VHH antibodies by tracking evolution of antibody along time course of immunization

The paper predicts antigen-reactive VHH antibodies by analyzing sequence evolution during immunization, achieving 75% accuracy in identifying antigen-responding clusters.

Molecular basis of egg coat cross-linking sheds light on ZP1-associated female infertility

The paper identifies ZP1 cross-linking as crucial for human ZP assembly and explores its modulation by fucosylation and zinc sparks, suggesting it as a target for non-hormonal contraception.

Sufficient therapeutic effect of cryopreserved frozen adipose-derived regenerative cells on burn wounds

This study shows that cryopreserved adipose-derived regenerative cells (ADRCs) are as effective as fresh ADRCs in promoting burn wound healing.

Repeated inversions at the pannier intron drive diversification of intraspecific colour patterns of ladybird beetles

The paper identifies pannier as a key regulatory gene for color pattern variation in ladybird beetles and shows that inversions and cis-regulatory changes at this gene drive intraspecific diversity.

In vivo monitoring of plant small GTPase activation using a Förster resonance energy transfer biosensor

This paper describes a protocol for monitoring plant small GTPase activation using a FRET biosensor in living plant cells.

Concept and in-silico assessment of an algorithm for monitoring cytosolic fluorescent aggregates in cells.

The paper introduces an algorithm for semi-automatic detection and segmentation of spot-like structures in fluorescence images, demonstrating its robustness in simulated and experimental conditions.