Author

K. Y. Sarin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. J. Bardwell· 1 shared A. L. S. Chang· 1 shared A. T. Satpathy· 1 shared B. Wu· 1 shared C. Curtis· 1 shared C. Wang· 1 shared D. K. Wells· 1 shared H. Y. Chang· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. J. Bardwell

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2 papers

Recent·Most cited

ERK2 MAP kinase regulates SUFU binding by multisite phosphorylation of GLI1

A. J. Bardwell, B. Wu, K. Y. Sarin, M. L. Waterman, S. X. Atwood, L. Bardwell

This study shows that ERK2 phosphorylates GLI1 at three sites, weakening its binding to SUFU and enhancing GLI1 activation, contributing to Hedgehog-MAPK pathway crosstalk in cancer.

bioRxiv · Dec 22, 2021Cell Biology

Clonal replacement of tumor-specific T cells following PD-1 blockade

K. E. Yost, A. T. Satpathy, D. K. Wells, Y. Qi, C. Wang, R. Kageyama, K. McNamara, J. M. Granja, K. Y. Sarin, R. A. Brown, R. K. Gupta, C. Curtis, S. L. Bucktrout, M. M. Davis, A. L. S. Chang, H. Y. Chang

This study tracks T cell clonal dynamics before and after PD-1 blockade in cancer patients, finding that new T cell clones, not pre-existing ones, expand in response to treatment.

bioRxiv · May 24, 2019Immunology