Author

Karen Davey

Hammersmith HospitalPrimary ORCID profile (0009-0007-3582-843X · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Karen DaveyiD2 papers · King's College London

Biology Disciplines

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Neuroscience· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:scRNA-seq· 3 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Aisling McGarryiD· 2 shared Amy M. SmithiD· 2 shared Combiz KhozoieiD· 2 shared David R. OweniD· 2 shared Nurun Nahar FancyiD· 2 shared Paul McMahan MatthewsiD· 2 shared Robert C. J. Muirhead· 2 shared Stergios TsartsalisiD· 2 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Aisling McGarryORCID

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3 papers

Recent·Most cited

Single nuclear transcriptional signatures of dysfunctional brain vascular homeostasis in Alzheimer's disease

Stergios Tsartsalis, Hannah Sleven, Nurun Nahar Fancy, Frank Wessely, Amy M. Smith, Nanet Willumsen, To Ka Dorcas Cheung, Michal Rokicki, Vicky M. N. Chau, Eseoghene Ifie, Combiz Khozoie, Olaf Ansorge, Xin Yang, Marion H. Jenkyns, Karen Davey, , Paul McMahan Matthews

The paper identifies transcriptional signatures in vascular cells from Alzheimer's disease brains, revealing dysregulated pathways linked to vascular dysfunction and immune activation.

Nature Communications · Mar 12, 2024Peer-reviewedNeuroscience

Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology

Amy M. Smith, Karen Davey, Stergios Tsartsalis, Combiz Khozoie, Nurun Nahar Fancy, See Swee Tang, Eirini Liaptsi, Maria Weinert, Aisling McGarry, Robert C. J. Muirhead, Steve Gentleman, David R. Owen, Paul McMahan Matthews

This study uses single-nuclei RNA sequencing to analyze astrocyte and microglial transcriptomes in Alzheimer's disease brains, identifying gene expression differences linked to amyloid-beta and phospho-tau pathology.

Acta Neuropathologica · Nov 12, 2021Peer-reviewedNeuroscience

A flexible microfluidic system for single-cell transcriptome profiling elucidates phased transcriptional regulators of cell cycle

Karen Davey, Daniel Wong, Filip A. Konopacki, Eugene Kwa, Tony Ly, Heike Fiegler, Christopher R. Sibley

The paper introduces a microfluidic system for single-cell transcriptome profiling and demonstrates its ability to identify cell cycle regulators.

Scientific Reports · Apr 12, 2021Peer-reviewedGenomics