Author

C. S. Calfee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:deep learning· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. R. Langelier· 3 shared D. J. Erle· 3 shared M. F. Krummel· 3 shared P. G. Woodruff· 3 shared B. Greenhouse· 2 shared C. M. Hendrickson· 2 shared The UCSF COMET Consortium· 2 shared A. A. Rao· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersImmunology

C. R. Langelier

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immediate myeloid depot for SARS-CoV-2 in the human lung

M. Magnen, R. You, A. A. Rao, R. T. Davis, L. Rodriguez, C. R. Simoneau, L. Hysenaj, K. H. Hu, The UCSF COMET Consortium, C. Love, P. G. Woodruff, D. J. Erle, C. M. Hendrickson, C. S. Calfee, M. A. Matthay, , M. R. Looney

The paper investigates early SARS-CoV-2 infection in human lung myeloid cells, finding rapid viral tropism, ACE2 dependence, and poor interferon induction, suggesting a myeloid depot for viral persistence.

bioRxiv · Apr 28, 2022Immunology

A conserved immune trajectory of recovery in hospitalized COVID-19 patients

T. L. H. Okholm, C. E. Burnett, I. Tenvooren, D. M. Marquez, S. Tamaki, P. M. Sandoval, The UCSF COMET Consortium, C. S. Calfee, C. M. Hendrickson, K. N. Kangelaris, C. R. Langelier, M. F. Krummel, P. G. Woodruff, D. J. Erle, K. M. Ansel, M. H. Spitzer

The paper identifies a conserved immune recovery trajectory in hospitalized COVID-19 patients through longitudinal mass cytometry analysis, linking immune processes to clinical outcomes.

bioRxiv · Mar 15, 2022 · PreprintImmunology

Longitudinal single-cell epitope and RNA-sequencing reveals the immunological impact of type 1 interferon autoantibodies in critical COVID-19

M. G. P. van der Wijst, S. E. Vazquez, G. C. Hartoularos, P. Bastard, T. Grant, R. Bueno, D. S. Lee, J. R. Greenland, Y. Sun, R. Perez, A. Ogorodnikov, A. Ward, S. A. Mann, K. L. Lynch, C. Yun, , C. R. Langelier

The paper examines IFN-I autoantibodies in critical COVID-19 patients through longitudinal single-cell analysis, revealing suppressed ISG-I responses in myeloid cells.

bioRxiv · Mar 9, 2021 · PreprintImmunology

FLASH: A next-generation CRISPR diagnostic for multiplexed detection of antimicrobial resistance sequences

J. Quan, C. Langelier, A. Kuchta, J. Batson, N. Teyssier, A. Lyden, S. Caldera, A. McGeever, B. Dimitrov, R. King, J. Wilheim, M. Murphy, L. Pesce Ares, K. A. Travisano, R. Sit, , E. D. Crawford

FLASH is a CRISPR-based diagnostic method that enhances detection of low-abundance antimicrobial resistance sequences in metagenomic data.

bioRxiv · May 12, 2019Microbiology