Author

Lauren Harris

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 5

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Fangfang QiiD· 2 shared Koichiro HaruwakaiD· 2 shared Long‐Jun WuiD· 2 shared Qi WuiD· 2 shared Yong HaniD· 2 shared Aastha DheeriD· 1 shared Abhijeet S. BarathiD· 1 shared Alireza SoltaniiD· 1 shared

Activity by Year

2019-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersNeuroscience

Fangfang QiORCID

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5 papers

Recent·Most cited

Microglial SWELL1 Deficiency Drives Male-Specific Seizure Vulnerability but Paradoxical Neuroprotection through Impaired Phagocytosis

Abhijeet S. Barath, Aastha Dheer, Laura Montier, Mekenzie M Peshoff, Emily C. Dale, Flavia Goche, Thanh Thanh L. Nguyen, Mastura Akter, Fangfang Qi, Dimitrios Kleidonas, Lauren Harris, Sarah A. Jewanee, Anthony D. Umpierre, Dale B. Bosco, Koichiro Haruwaka, , Long‐Jun Wu

This study shows that microglial SWELL1 deficiency increases male-specific seizure severity but protects neurons through impaired phagocytosis and reduced neuroactive metabolite release.

JCI Insight · Jun 21, 2026Peer-reviewedNeuroscience

Cortical microglia promote noradrenergic signaling to maintain wakefulness

Yue Liang, Wu Shi, Emily M. Dale, Shunyi Zhao, Fangfang Qi, Koichiro Haruwaka, Qixiu Hou, Mengdi Fei, Lauren Harris, Xiaoyang Hua, Long-jun Wu

This study shows that microglia interact with noradrenergic axons in the frontal cortex, enhancing norepinephrine transmission and supporting wakefulness.

bioRxiv · Dec 27, 2025 · PreprintNeuroscience

Reversal of Obesity by Enhancing Slow-wave Sleep via a Prokineticin Receptor Neural Circuit

Yong Han, Guobin Xia, Lauren Harris, Panpan Liu, Dongyin Guan, Qi Wu

This study identifies a neural circuit linking appetite and sleep regulation, showing that targeting it with pterostilbene reduces obesity and improves sleep in diet-induced obese mice.

bioRxiv · Apr 30, 2024 · PreprintNeuroscience

Reversal of obesogenic feeding and hypometabolism by a bifurcating GABAergic neural circuit

Yong Han, Yang He, Lauren Harris, Yong Xu, Qi Wu

This study identifies two distinct GABAergic neural circuits in the hypothalamus that differentially regulate metabolic homeostasis and obesogenic feeding through specific GABAA receptor signaling pathways.

eLife · Mar 27, 2023Peer-reviewedNeuroscience

Influence of expected reward on perceptual decision making

Mohsen Rakhshan, Vivian Lee, Emily K. Chu, Lauren Harris, Lillian Laiks, Peyman Khorsand, Alireza Soltani

This study investigates how expected reward influences perceptual decision making and finds that reward effects are better explained by decision-making processes rather than sensory processing.

bioRxiv · Jul 11, 2019 · PreprintNeuroscience