Author

Lee B Barrett

Boston Children's Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Clifford J. WoolfiD· 3 shared Akie FujitaiD· 1 shared Biyao ZhangiD· 1 shared Bruce P. BeaniD· 1 shared Bruna Lenfers TurnesiD· 1 shared Christopher V. GabeliD· 1 shared Daniel G. TaubiD· 1 shared Daniel H. GeschwindiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersNeuroscience

Clifford J. WoolfORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ARBEL: A Machine Learning Tool with Light-Based Image Analysis for Automatic Classification of 3D Pain Behaviors

Omer Barkai, Biyao Zhang, Bruna Lenfers Turnes, Maryam Arab, David A. Yarmolinsky, Zihe Zhang, Lee B Barrett, Clifford J. Woolf

ARBEL automatically classifies 3D pain behaviors in mice using light-based analysis and pose estimation, achieving high precision and enabling efficient drug screening.

Cell Reports Methods · Aug 27, 2025Peer-reviewedNeuroscience

Cannabidiol activates neuronal Kv7 channels

Han-Xiong Bear Zhang, Laurel M. Heckman, Zachary Niday, Sooyeon Jo, Akie Fujita, Jaehoon Shim, Roshan Pandey, Hoor Al Jandal, Selwyn S. Jayakar, Lee B Barrett, Jennifer A. Smith, Clifford J. Woolf, Bruce P. Bean

This study identifies CBD's activation of Kv7 channels as a mechanism for its antiepileptic effects.

eLife · Feb 10, 2022Peer-reviewedNeuroscience

Screening for axon regeneration promoting compounds with human iPSC-derived motor neurons

Tammy Szu‐Yu Ho, J. Tabitha Hees, Zhuqiu Xu, Riki Kawaguchi, Natália P. Biscola, Daniel G. Taub, Kuchuan Chen, Xirui Chen, Lee B Barrett, Long Cheng, Christopher V. Gabel, Leif A. Havton, Daniel H. Geschwind, Clifford J. Woolf

This study identifies compounds that promote axon regeneration using human iPSC-derived motor neurons and validates blebbistatin as a top hit in vivo.

bioRxiv · Nov 2, 2021 · PreprintNeuroscience