M. E. Feeney

Broadly inhibitory antibodies against severe malaria virulence proteins

The paper identifies two human monoclonal antibodies that broadly inhibit PfEMP1's binding to EPCR, a key process in severe malaria pathogenesis.

Distinct transcriptional profiles of maternal and fetal placental macrophages at term are associated with gravidity

The paper compares transcriptional profiles of maternal and fetal placental macrophages in term pregnancies, finding distinct gene expression patterns linked to gravidity.

Disease Tolerance Acquired Through Repeated Plasmodium Infection Involves Epigenetic Reprogramming of Innate Immune Cells

The paper shows that repeated Plasmodium infection leads to epigenetic changes in innate immune cells, which suppress inflammation and confer long-term disease tolerance in Ugandan children.

Atypical B cells consist of subsets with distinct effector functions

The paper identifies three distinct subsets of atypical B cells with unique transcriptional and functional profiles in individuals with chronic Plasmodium falciparum exposure.

In Utero Activation of NK Cells in Congenital CMV Infection

The paper examines NK cell activation in congenital CMV infection by analyzing cord blood samples from infected and uninfected newborns, finding increased cytotoxicity and maturation in infected infants.

Distinct cellular immune signatures in acute Zika virus infection are associated withhigh or low persisting neutralizing antibody titers

The paper uses mass cytometry to identify immune cell signatures in acute ZIKV infection that predict high or low neutralizing antibody titers 6 months post-infection.