M. Fukushima

Internal structure of Mycoplasma mobile gliding machinery analyzed by negative staining electron tomography

This study uses electron tomography to analyze the internal structure of Mycoplasma mobile gliding machinery, revealing motor complexes and structural components involved in gliding.

Maternal high-fat diet affects the contents of eggs and causes abnormal development in the medaka fish

This study shows that maternal high-fat diet in medaka fish leads to egg content changes and increased embryonic deformities in offspring.

Functionally conserved Pkd2, mutated in autosomal dominant polycystic kidney disease, localizes to the endoplasmic reticulum and regulates cytoplasmic calcium homeostasis in fission yeast

This study shows that Pkd2, a homolog of human polycystin-2, localizes to the ER and regulates calcium homeostasis in fission yeast, with functional conservation between species.

Creation of X-linked Alport Syndrome Rat Model with Col4a5 Deficiency

This study creates a novel Alport syndrome rat model with Col4a5 deficiency to better understand renal disease mechanisms and therapeutic targets.

Mucin O-glycans facilitate symbiosynthesis to maintain gut immune homeostasis

This study identifies mucin O-glycans as a fermentation substrate for n-butyrate production, which supports immune homeostasis in the gut.

The p21 dependent G2 arrest of the cell cycle in epithelial tubular cells links to the early stage of renal fibrosis

The paper identifies p21-dependent G2 cell cycle arrest in proximal tubular cells as an early response to renal damage, which may protect kidney function during the initial stage of fibrosis.