Author

M. W. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

A. Garcia-Sastre· 3 shared C. Benner· 3 shared L. Pache· 3 shared J. F. Hultquist· 2 shared S. Chanda· 2 shared A. Artati· 1 shared A. Cazenave-Gassiot· 1 shared A. Jerzy· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. Garcia-Sastre

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

MFSD7c functions as a transporter of choline at the blood-brain barrier

X. T. A. Nguyen, U. T. N. Le, H. T. T. Ha, T. Q. Nguyen, A. Artati, N. C. P. Leong, D. T. Nguyen, P. Y. Lim, A. V. Susanto, Q. Huang, L. Fam, N. L. Leong, I. Bonne, A. Lee, C. Gooch, , L. N. Nguyen

This study identifies MFSD7c as a choline transporter at the blood-brain barrier and links its dysfunction to Fowler syndrome.

bioRxiv · Oct 3, 2023Biochemistry

Breakthrough infections by SARS-CoV-2 variants boost cross-reactive hybrid immune responses in mRNA-vaccinated Golden Syrian Hamsters

J. Garcia-Bernalt Diego, G. Singh, S. Jangra, K. Handrejk, M. Laporte, L. A. Chang, S. S. El Zahed, L. Pache, M. W. Chang, P. Warang, S. Aslam, I. Mena, B. T. Webb, C. Benner, A. Garcia-Sastre, M. Schotsaert

This study evaluates hybrid immunity in mRNA-vaccinated hamsters during breakthrough infections, finding enhanced cross-reactive immune responses despite low neutralizing antibody titers.

bioRxiv · May 22, 2023Microbiology

Type I IFN promotes pathogenic inflammatory monocyte maturation during H5N1 infection

S. Fourati, D. Jimenez-Morales, J. F. Hultquist, M. W. Chang, C. Benner, N. J. Krogan, L. Pache, S. Chanda, R.-P. Sekaly, A. Garcia-Sastre, M. B. Uccellini

This study shows that type I IFN promotes the maturation of inflammatory monocytes into pathogenic FasL+MCs during H5N1 infection, contributing to disease severity.

bioRxiv · Jan 10, 2022 · PreprintImmunology

Functional Landscape of SARS-CoV-2 Cellular Restriction

L. Martin-Sancho, M. K. Lewinski, L. Pache, C. Stoneham, X. YIN, D. Pratt, C. Churas, S. B. Rosenthal, S. Liu, P. D. De Jesus, A. M. O'Neill, A. P. Gounder, C. Nguyen, Y. Pu, A. L. Oom, , S. Chanda

This study identifies key interferon stimulated genes (ISGs) that restrict SARS-CoV-2 infection by inhibiting viral entry, RNA synthesis, and release.

bioRxiv · Sep 29, 2020Microbiology