M. Wang

This study identifies the molecular mechanisms and post-translational modifications governing the generation of distinct Nrf1α/TCF11 proteoforms and their involvement in feedback circuits with regulatory proteins.

This study identifies the oxidative enzyme systems in Polyporus brumalis that enable efficient lignin degradation during wheat straw fermentation.

This study identifies topovectorial mechanisms that control Nrf1 proteolytic processing to generate mature CNC-bZIP transcription factor isoforms through ER-associated degradation.

The paper presents three cryo-EM structures of pancreatic KATP channels, revealing drug binding sites, subunit interactions, and conformational changes related to metabolic regulation.

This study identifies AMPKi as a compound that blocks 14-3-3 binding to CRAF, overcoming RAF inhibitor resistance by preventing paradoxical CRAF activation in cancer cells.

This study investigates the genomic features and evolution of a conditionally dispensable chromosome (CDC) in the tangerine pathotype of Alternaria alternata, revealing its role in pathogenicity and horizontal gene transfer.

The paper shows that EZH1 and EZH2, two catalytic subunits of PRC2, are differentially activated to regulate H3K27 methylation, with AEBP2 adding additional stimulation.

This study identifies mitochondrial dysfunction and metabolic dysregulation as factors underlying poor muscle recovery in old mice after hind limb unloading.