Meera V. Sundaram

The paper identifies LPR-3 and WRT-10 as functional partners in the C. elegans pre-cuticle apical extracellular matrix, showing their interaction patterns and roles in matrix organization.

The paper shows that apical spectrin organizes actin filament bundles in C. elegans to pattern cuticle ridges, and its loss disrupts ridge formation and matrix delamination.

The paper shows DPY-6 guides periodic furrow formation in C. elegans cuticle by acting as a molecular mold during molts.

This study shows that lipocalin LPR-1 and scavenger receptor SCAV-2 have opposing roles in maintaining the apical extracellular matrix of narrow tubes in C. elegans.

This study identifies FGF-dependent, polarized SOS activity as a mechanism for directing C. elegans muscle progenitor migration, independent of canonical RTK effectors.

The paper investigates how the Pax transcription factor EGL-38 regulates cell-type specific assembly of the apical extracellular matrix in C. elegans vulva cells.

This study shows that the idh-1neo mutation in C. elegans increases dependency on one-carbon metabolism, making the worms vulnerable to vitamin B12 deficiency and leading to embryonic lethality.

This study identifies C. elegans Hedgehog-related proteins as components of the cuticle and pre-cuticle extracellular matrices, showing tissue- and substructure-specific associations and functional roles in matrix structure.

The paper shows how actin and a provisional matrix work together to shape acellular ridges in C. elegans cuticle through transient actomyosin constriction and matrix patterning.

This study shows that the ZPc domain of LET-653 in C. elegans is primarily responsible for aECM assembly and tissue shaping, contradicting current models that emphasize the ZPn domain.

The paper describes the dynamic apical extracellular matrix in C. elegans vulva, showing its role in shaping the lumen through distinct molecular components and genetic regulation.