Author

N. Bluethgen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1 Ecology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Assay:DNA methylation· 1

Frequent Co-Authors

C. Sers· 2 shared M. M. Fischer· 2 shared M. Morkel· 2 shared P. Riemer· 2 shared A. D. Gruber· 1 shared A. Di Domenico· 1 shared A. Jarosch· 1 shared A. Menne· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersCancer Biology

C. Sers

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Single-cell-resolved interspecies comparison identifies a shared inflammatory axis and a dominant neutrophil-endothelial program in severe COVID-19

S. Peidli, G. Nouailles, E. Wyler, J. M. Adler, S. Kunder, A. Voss, J. Kazmierski, F. Pott, P. Pennitz, D. Postmus, L. G. Teixeira Alves, C. Goffinet, A. D. Gruber, N. Bluethgen, M. Witzenrath, , S. D. Praktiknjo

The paper compares single-cell RNA-seq data from hamster and human COVID-19 samples to identify a shared inflammatory axis and a neutrophil-endothelial program associated with severe disease.

bioRxiv · Aug 25, 2023Immunology

On minimising tumoural growth under treatment resistance

M. M. Fischer, N. Bluethgen

This paper develops mathematical models to optimize cancer treatment protocols by analyzing genetic and epigenetic resistance, showing that an optimal protocol can achieve curative treatment in xenograft experiments.

bioRxiv · Jul 4, 2023Cancer Biology

Shifts from non-obligate generalists to obligate specialists in simulations of mutualistic network assembly

T. Metz, N. Bluethgen, B. Drossel

The paper simulates mutualistic network assembly showing non-obligate generalists facilitate early stages while obligate specialists dominate later stages.

bioRxiv · Aug 4, 2022Ecology

Maintaining and escaping feedback control in hierarchically organised tissue: a case study of the intestinal epithelium

M. M. Fischer, H. Herzel, N. Bluethgen

The paper presents a mathematical model of intestinal epithelium dynamics showing how feedback control maintains homeostasis and enables recovery from perturbations.

bioRxiv · Jun 11, 2021 · PreprintCancer Biology

DNA methylation reveals distinct cells of origin for pancreatic neuroendocrine carcinomas (PanNECs) and pancreatic neuroendocrine tumors (PanNETs)

T. Simon, P. Riemer, K. Detjen, A. Di Domenico, F. Bormann, A. Menne, S. Khouja, N. Monje, L. H. Childs, D. Lenze, U. Leser, A. Jarosch, F. Rossner, M. Morkel, N. Bluethgen, , C. Sers

The paper uses DNA methylation analysis to distinguish high-grade PanNECs from other PanNETs, revealing an exocrine cell of origin for PanNECs.

bioRxiv · Jun 12, 2020Cancer Biology

Cell type-dependent differential activation of ERK by oncogenic KRAS in colon cancer and intestinal epithelium

R. Brandt, T. Sell, M. Luethen, F. Uhlitz, B. Klinger, P. Riemer, C. Giesecke, S. Schulze, I. A. El-Shimy, D. Kunkel, B. Fauler, T. Mielke, N. Mages, B. G. Herrmann, C. Sers, , M. Morkel

The paper investigates how oncogenic KRAS and BRAF differentially activate ERK in colon cancer and intestinal epithelium, revealing cell type-specific effects and novel regulatory mechanisms.

bioRxiv · Feb 14, 2019Cell Biology