Author

N. Xing

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Evolutionary Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 4 Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

H. Wu· 4 shared B. Fu· 3 shared D. Kunec· 3 shared J. Trimpert· 3 shared W. Xue· 3 shared X. Lin· 3 shared G. Meng· 2 shared K. Meng· 2 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMicrobiology

H. Wu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A live attenuated vaccine confers superior mucosal and systemic immunity to SARS-CoV-2 variants

G. Nouailles, J. M. Adler, P. Pennitz, S. Peidli, G. Teixeira Alves, M. Baumgart, J. Bushe, A. Voss, A. Langenhagen, F. Pott, J. Kazmierski, C. Goekeri, S. Simmons, N. Xing, C. Langner, , J. Trimpert

This study compares immune responses and efficacy of different SARS-CoV-2 vaccines in hamsters, finding that a live-attenuated vaccine provides superior protection against variants.

bioRxiv · May 16, 2022Immunology

Nucleocapsid 203 mutations enhance SARS-CoV-2 immune evasion

X. Lin, W. Xue, Y. Zhang, B. Fu, J. Trimpert, N. Xing, D. Kunec, W. Tang, Y. Xiao, K. Meng, S. Shi, H. Wu, G. Meng, Z. Zhu

This study shows that the nucleocapsid 203 mutation, combined with spike L452R, enhances SARS-CoV-2 immune evasion and fitness, contributing to the dominance of variants like Delta and Omicron.

bioRxiv · Dec 20, 2021 · PreprintMicrobiology

Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection

X. Lin, B. Fu, Y. Xiong, N. Xing, W. Xue, D. Guo, M. Y. Zaky, K. C. Pavani, D. Kunec, J. Trimpert, H. Wu

This study identifies unconventional secretion of unglycosylated ORF8 as critical for inducing cytokine storms during SARS-CoV-2 infection by interacting with IL17RA on macrophages.

bioRxiv · Dec 3, 2021Microbiology

Nucleocapsid mutation R203K/G204R increases the infectivity, fitness and virulence of SARS-CoV-2

H. Wu, N. Xing, K. Meng, B. Fu, W. Xue, P. Dong, Y. Xiao, G. Liu, H. Luo, W. Zhu, X. Lin, G. Meng, Z. Zhu

This study shows that the N protein mutations R203K/G204R increase SARS-CoV-2 infectivity, replication, and virulence, contributing to its spread and disease severity.

bioRxiv · May 24, 2021Evolutionary Biology