Author

Ning-Sum To

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Assay:proteomics· 3 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Andrew C. YangiD· 3 shared Ian Hunter GuldneriD· 3 shared Sophia M. ShiiD· 3 shared Tom H. CheungiD· 3 shared Tony Wyss‐CorayiD· 3 shared Andreas KelleriD· 2 shared Jian LuoiD· 2 shared Nannan LuiD· 2 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Andrew C. YangORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Domain-specific proteome remodeling defines mouse myelin aging

Yarden Freund, Michael Schoof, Noa Moreno, Florian Kriegel, Heather Shin, Vanessa Waelchli, Achint Kaur, Kevin Abraham, Ido Fogel, Sophia M. Shi, Ning-Sum To, Ian Hunter Guldner, Tom H. Cheung, Andrew C. Yang, Andreas Keller, , Tal Iram

This study identifies age- and sex-related changes in the mouse myelin proteome, revealing increased structural proteins and decreased cytoskeletal and synaptic proteins with aging.

bioRxiv · Jul 9, 2026 · PreprintNeuroscience

Synaptic proteins that aggregate and degrade slower with aging accumulate in microglia

Ian Hunter Guldner, Viktoria Wagner, Patricia Morán Losada, Sophia M. Shi, Kelly S. Chen, Barbara T Meese, Hamilton Se‐Hwee Oh, Yann Le Guen, Nannan Lu, Pui Shuen Wong, Ning-Sum To, Dylan T. Garceau, Zimin Guo, Jian Luo, Michael Sasner, , Tony Wyss‐Coray

The paper identifies neuronal proteins that degrade slower with aging and accumulate in microglia, linking impaired synaptic protein turnover to age-related cognitive decline.

bioRxiv · May 20, 2025 · PreprintNeuroscience

Circulatory proteins shape microglia state and boost phagocytosis

Nannan Lu, Patricia Morán Losada, Oliver Hahn, Aryaman Saksena, Emma Tapp, Jean Paul Chadarevian, Wentao Dong, Sophia M. Shi, Steven R. Shuken, Ian Hunter Guldner, Wenshu Zeng, Ning-Sum To, Pui Shuen Wong, Jonathan Hasselmann, Hayk Davtyan, , Tony Wyss‐Coray

The paper identifies a microglia population that takes up circulatory proteins, enhancing phagocytosis and innate immunity through ApoA-I uptake.

bioRxiv · Sep 30, 2024 · PreprintNeuroscience