Author
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4 papers
Recent·Most cited
E. Forsgren, O. Cloarec, P. Jonsson, J. Trygg
The paper introduces a scalable data analytics workflow for interpreting high-dimensional image-based morphological data to improve drug screening efficiency.
Chemometrics and Intelligent Laboratory Systems · Nov 1, 2024Peer-reviewedCell Biology
J. M. Weiss, M. V. Hunter, N. M. Cruz, A. Baggiolini, M. Tagore, Y. Ma, S. Misale, M. Marasco, T. Simon-Vermot, N. R. Campbell, F. Newell, J. S. Wilmott, P. A. Johansson, J. F. Thompson, G. V. Long, , R. M. White
The paper shows that anatomic position influences oncogenic specificity in melanoma by identifying position-specific gene programs that interact with oncogenes like CRKL.
bioRxiv · Nov 14, 2020Cancer Biology
R. A. Fernandes, K. A. Ganzinger, J. Tzou, P. Jonsson, S. F. Lee, M. Palayret, A. M. Santos, A. A. Carr, A. Ponjavic, V. T. Chang, C. Macleod, B. C. Lagerholm, A. E. Lindsay, O. Dushek, A. Tilevik, , D. Klenerman
This paper develops a model showing T-cell receptors discriminate ligands based on dwell-time in phosphatase-depleted contacts constrained by cell topography, predicting signaling potency without multi-step proof-reading.
bioRxiv · Nov 19, 2018Immunology
V. Junghans, J. Hladilkova, A. M. Santos, M. Lund, S. J. Davis, P. Jonsson
The paper introduces hydrodynamic trapping to measure membrane protein interaction potentials and shows how protein shape, glycosylation, and flexibility affect their behavior.
bioRxiv · Jun 30, 2018Biophysics