Author

Ravindra Amunugama

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

Davood NorouziiD· 3 shared Jonathan D. FinniD· 3 shared Kaivalya MoluguiD· 3 shared Sandeep KumariD· 3 shared Anne M. Bara· 2 shared Brett EstesiD· 2 shared Chong T. LuoiD· 2 shared Connor McGinnis· 2 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Davood NorouziORCID

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Author profile →

3 papers

Recent·Most cited

Highly Efficient Multiplexed Genome Engineering and Clone Selection to Enable Next Generation Induced Pluripotent Stem Cell (iPSC)-based Cell Therapies

Kaivalya Molugu, Ruba Halaoui, Mohammed Zeaiter, Anne M. Bara, Matthew H. Bakalar, Bruna Castro de Oliveira, Connor McGinnis, Jie Wang, Marie-Joe Kimaz, Lauren Herchenroder, Arun Bhattathiri, Alexander Allen, Minggang Fang, Davood Norouzi, Didac Santesmasses, , Chong T. Luo

This paper introduces a novel genome engineering method for iPSCs that enables efficient multiplex gene editing and clone selection, improving the precision and speed of iPSC-based therapies.

bioRxiv · Dec 25, 2025 · PreprintGenomics

Ligase-mediated programmable genomic integration (L-PGI): an efficient site-specific gene editing system that overcomes the limitations of reverse transcriptase-based editing systems

Angela X. Nan, Michael Chickering, Christopher L. Bartolome, Neeta Shadija, Dan Li, Brett Estes, Jessica R. Von Stetina, Wei Li, Jason L. Andresen, Kaivalya Molugu, Ravindra Amunugama, Minggang Fang, Chen Bai, Jie Wang, Davood Norouzi, , Jenny Xie

This paper introduces L-PGI, a ligase-mediated gene editing system that enables efficient and precise genomic integration in both dividing and nondividing cells, overcoming limitations of reverse transcriptase-based methods.

Nature Communications · Dec 10, 2025Peer-reviewedBioengineering

Large Serine Integrase Off-target Discovery and Validation for Therapeutic Genome Editing

Dane Z. Hazelbaker, Japan B. Mehta, Connor McGinnis, Didac Santesmasses, Anne M. Bara, Xiaoyu Liang, Thomas C. Biondi, Tim J. Fennell, Nils Homer, Brett Estes, Jenny Xie, Davood Norouzi, Kaivalya Molugu, Ravindra Amunugama, Chong T. Luo, , Daniel J. O’Connell

The paper develops and validates methods to detect off-target recombination by Large Serine Integrases, finding higher sensitivity than whole genome sequencing.

bioRxiv · Aug 23, 2024 · PreprintGenomics