Onur Başak

Regional specificity of neuronal cell types, functional connectivity, and cell type-specific correlation to brain disorders in the human ventral tegmental area

This study creates a transcriptomic atlas of the human ventral tegmental area, identifies cell types and their functional connectivity, and links them to psychiatric disorders and BMI.

Unique transcriptional profiles of adult human immature neurons in healthy aging, Alzheimer's disease, and cognitive resilience

The paper identifies unique transcriptional profiles of immature neurons in aged human hippocampus across healthy, Alzheimer's disease, and resilient conditions, linking them to homeostasis and cognitive resilience.

MeCP2 binding and genome-lamina reorganization precede long gene activation during mouse corticogenesis

The paper identifies genome-lamina reorganization preceding long gene activation in mouse corticogenesis and links it to MeCP2 binding.

Molecular Signatures and Cellular Diversity During Mouse Habenula Development

This study identifies molecular signatures and cellular diversity during mouse habenula development using single-cell transcriptomics and links developmental subtypes to psychiatric disease.

Resolving the transcriptional transitions associated with oligodendrocyte generation from adult neural stem cells by single cell sequencing

The paper uses single-cell transcriptomics to study the transcriptional changes during oligodendrocyte generation from adult neural stem cells in the SVZ, identifying key regulatory mechanisms and signaling pathways involved.

Single-cell analysis reveals cellular heterogeneity and molecular determinants of hypothalamic leptin-receptor cells

The paper uses scRNA-seq to analyze LepR cells in the hypothalamus, identifying eight neuronal clusters and 17 non-neuronal populations, and finds enrichment of obesity GWAS signals in multiple clusters.