Author

S. Caldwell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1

Frequent Co-Authors

A. Falzone· 2 shared G. M. DeNicola· 2 shared N. Prieto-Farigua· 2 shared A. A. Gheorghita· 1 shared A. Antanasijevic· 1 shared A. J. Borst· 1 shared A. J. R. Heck· 1 shared A. Khmelinskaia· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

A. Falzone

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Local structural flexibility drives oligomorphism in computationally designed protein assemblies

A. Khmelinskaia, N. P. Bethel, F. Fatehi, A. Antanasijevic, A. J. Borst, S.-H. Lai, J. Y. Wang, B. Basu Mallik, M. M. Miranda, A. M. Watkins, C. Ogohara, S. Caldwell, M. Wu, A. J. R. Heck, D. Veesler, , N. P. King

This study shows that structural flexibility in computationally designed protein assemblies leads to multiple architectures, expanding their functional possibilities.

bioRxiv · Oct 18, 2023Bioengineering

Pseudomonas aeruginosa AlgF is a protein-protein interaction mediator required for acetylation of the alginate exopolysaccharide

K. Low, A. A. Gheorghita, S. Tammam, G. B. Whitfield, Y. E. Li, L. M. Riley, J. Weadge, S. Caldwell, P. A. Chong, M. Walvoort, E. Kitova, J. Klassen, P. L. Howell

This study identifies AlgF as a protein-protein interaction mediator in Pseudomonas aeruginosa that facilitates the formation of an acetylation and export complex for alginate modification.

bioRxiv · Jul 25, 2023Microbiology

The Origin Of Cysteine and its Catabolism in Mammalian Tissues and Tumors

S. J. Yoon, J. A. Combs, A. Falzone, N. Prieto-Farigua, S. Caldwell, H. D. Ackerman, E. R. Flores, G. M. DeNicola

This study investigates cysteine metabolism in normal and tumor tissues using isotopic tracing, finding that cystine uptake is universal while de novo synthesis and catabolism vary across tissues and tumor types.

bioRxiv · Aug 26, 2022Cancer Biology

Distinct Nrf2 Signaling Thresholds Mediate Lung Tumor Initiation and Progression

J. M. DeBlasi, A. Falzone, S. Caldwell, N. Prieto-Farigua, J. R. Prigge, E. E. Schmidt, I. I. C. Chio, F. A. Karreth, G. M. DeNicola

This study investigates the role of Nrf2 signaling thresholds in lung tumor initiation and progression using murine models with KEAP1 and NRF2 mutations.

bioRxiv · Aug 24, 2022Cancer Biology

Rv3723/LucA coordinates fatty acid and cholesterol uptake in Mycobacterium tuberculosis

B. C. VanderVen, E. V. Nazarova, C. R. Montague, T. La, K. M. Wilburn, N. Sukumar, W. Lee, S. Caldwell, D. G. Russell

This study identifies LucA as a coordinator of cholesterol and fatty acid uptake in Mtb, linking these processes to bacterial virulence.

bioRxiv · Mar 29, 2017Microbiology