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Primary ORCID profile (0000-0001-6148-457X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
8 papers
Recent·Most cited
E. Spears, J. E. Stanley, M. Shou, C. Dai, A. Bradley, L. Yin, X. Li, K. Sellick, G. Poffenberger, K. C. Coate, S. D. Shrestha, R. Jenkins, K. Sloop, K. T. Wilson, A. D. Attie, , E. D. Dean
This study identifies SLC7A2 as essential for α cell proliferation and glucagon secretion, linking arginine transport to metabolic regulation and HbA1c variation.
bioRxiv · Aug 10, 2023Physiology
J. J. Fan, X. Wang, A. W. Erickson, P. Skowron, X. Wang, X. Chen, G. Shan, S. Bahrampour, Y. Xiong, W. Dong, N. Abeysundara, M. A. Francisco, R. J. Pusong, R. A. Suarez, H. Farooq, , X. Huang
The paper identifies potassium homeostasis as essential for medulloblastoma maintenance using a novel transposon system in mice and human samples.
bioRxiv · Jul 23, 2022Cancer Biology
T. P. Martin, E. A. MacDonald, A. Bradley, H. Watson, P. Saxena, E. A. Rog-Zielinska, S. Fisher, A. A. M. Elbassioni, O. Almuzaini, C. Booth, M. Campbell, P. Herzyk, K. Blyth, C. Nixon, L. Zentilin, , C. M. Loughrey
This study shows that inhibiting RUNX1 improves heart function after myocardial infarction by preserving contractility and mitochondrial function.
bioRxiv · Feb 17, 2022 · PreprintPathology
B. Xue, C.-H. Chuang, H. M. Prosser, C. S. Fuziwara, C. Chan, N. Sahasrabudhe, M. Kühn, Y. Wu, J. Chen, A. Biton, C. Chen, J. E. Wilkinson, M. T. McManus, A. Bradley, M. M. Winslow, , L. He
This study shows that miR-200 deficiency in lung cancer cells promotes metastasis by activating cancer-associated fibroblasts through Notch signaling.
bioRxiv · Sep 2, 2020Cancer Biology
e. resnick, A. Bradley, J. Gan, A. Douangamath, T. Krojer, R. Sethi, A. Aimon, G. Amitai, D. Belini, J. Bennett, M. Fairhead, O. Fedorov, P. P. Geurink, J. Guo, A. Plotnikov, , N. London
This study develops a method for discovering covalent probes using electrophile fragment screening and identifies selective inhibitors for OTUB2 and NUDT7.
bioRxiv · Oct 14, 2018Biochemistry
G. Balmus, D. Pilger, J. Coates, M. Demir, M. Sczaniecka-Clift, A. Barros, M. Woods, B. Fu, F. Yang, E. Chen, M. Ostermaier, T. Stankovic, H. Ponstingl, M. Herzog, K. Yusa, , S. P. P. Jackson
The paper identifies how ATM counteracts toxic non-homologous end-joining at broken replication forks by showing that loss of NHEJ components or BRCA1-A complex confers resistance to DNA-damaging agents in ATM-deficient cells.
bioRxiv · May 24, 2018Cell Biology
A. Bradley, T. Hashimoto, M. Ono
This study uses single-cell RNA-seq and multidimensional analysis to show how TCR signals control the activation and differentiation of regulatory and effector T cells.
bioRxiv · Mar 19, 2018Immunology
D. Egli, M. Zuccaro, M. Kosicki, G. Church, A. Bradley, M. Jasin
The paper reviews the claim of inter-homologue repair in human embryos using CRISPR-Cas9 and discusses biological constraints and alternative explanations for the observed data.
bioRxiv · Aug 28, 2017Cell Biology