S. Franzenburg

FoxO factors preserve airway epithelial homeostasis by coordinating adaptive stress responses

The paper shows FoxO factors in Drosophila, mouse, and human airway epithelial cells respond to stressors by nuclear translocation, with FoxO-dependent stress pathways altered in asthma across species.

Antibiotic prophylaxis and hospitalization of horses subjected to median laparotomy: gut microbiota trajectories and abundance increase of Escherichia

This study examines the impact of peri-operative antibiotic prophylaxis on gut microbiota in horses undergoing median laparotomy, finding increased ESBL-producing bacteria and reduced diversity.

Persistent virus-specific and clonally expanded antibody secreting cells respond to induced self antigen in the CNS

The paper identifies virus-specific, clonally expanded antibody-secreting cells in the CNS that persist and respond to induced self-antigen, with parallels in multiple sclerosis patients.

High potency of sequential therapy with only beta-lactam antibiotics

This study shows that sequential therapy with only beta-lactam antibiotics can increase bacterial population extinction by reducing spontaneous resistance and cross-resistance.

Microbial strategies for survival in the glass sponge Vazella pourtalesii

This study identifies the microbial composition and functional strategies of the symbionts in the glass sponge Vazella pourtalesii, revealing two distinct microbial strategies adapted to low-oxygen conditions.

Maintaining structural and functional homeostasis of the Drosophila respiratory epithelia requires stress-modulated JAK/STAT activity

This study shows that balanced JAK/STAT signaling is essential for maintaining structural and functional homeostasis in Drosophila respiratory epithelia, while chronic overactivation leads to pathological changes resembling human lung diseases.

Deciphering a marine bone degrading microbiome reveals a complex community effort

This study identifies microbial enzymes and pathways involved in marine bone degradation using metagenomic analysis of bone-associated communities.

Ecological assembly processes of the bacterial and fungal microbiota of wild and domesticated wheat species

This study examines how domestication affects the ecological assembly of bacterial and fungal microbiota in wheat species, finding distinct community patterns and a greater role of neutral processes in domesticated wheat.

Somatic genetic drift and multi-level selection in modular species

The paper investigates somatic genetic variation in modular species, finding that clonal growth leads to genetically differentiated modules with varying levels of selection.

Neutrality in the Metaorganism

This study shows that microbiota community structure across various host organisms aligns with neutral model predictions, suggesting neutral processes rather than host selection primarily shape microbial communities after colonization.

Neolithic and Medieval virus genomes reveal complex evolution of Hepatitis B

This study analyzes three ancient HBV genomes from European skeletons, showing HBV circulation for 7000 years and distinct lineages that may have gone extinct.