S. Han

This study shows that S. thermophilus 19 reduces inflammation in septic mice by remodeling gut microbiota.

This study investigates how hepatitis C virus (HCV) infection affects choline metabolism in liver cells, showing that choline transport and metabolism are modulated during early infection, with varying effects depending on culture conditions.

This paper introduces a rapid antimicrobial susceptibility test using laser speckle dynamics to detect bacterial growth in 2-4.5 hours.

This study shows that fatty acid-induced lipotoxicity reduces choline uptake and PC synthesis in mouse hepatocytes, independent of ER stress.

This study develops a primary gill epithelial cell model from olive flounder to propagate VHSV, showing increased cell viability with higher fetal bovine serum concentration.

This study shows that tau's liquid-liquid phase separation and amyloid aggregation are independent processes that occur under overlapping conditions.

APEX-seq maps subcellular RNA localization with nanometer resolution, revealing nuclear transcriptome organization and mitochondrial mRNA pathways.

The paper identifies a Copia-family retrotransposon, RAC, within the Rhg1-encoded α-SNAP gene in rhg1-a soybean haplotypes, which is absent in rhg1-b and Rhg1WT soybeans.

This study determines the structure of TRPV2 bound to cannabidiol, revealing a unique binding site and the role of the S4-S5 linker in channel gating.

This study presents cryo-EM structures of the human glutamine transporter SLC1A5 in an outward-facing conformation, revealing insights into its transport mechanism and substrate recognition.

This study shows LonP1 regulates UPRmt and UPRER, and mitochondrial dynamics in cardiomyocytes, impacting heart function and revealing potential therapeutic targets for heart failure.

The paper determines the cryo-EM structure of the FXN-bound active human ISC biosynthesis complex, revealing how FXN activates NFS1 by removing zinc inhibition and stabilizing protein interfaces.

This paper identifies rare germline mutations associated with triple-negative breast cancer risk using a machine learning approach and shows improved risk prediction compared to existing methods.

This study identifies the narrow conditions under which tau and RNA form reversible coacervates and fibrils, revealing entropy-driven LLPS under physiological conditions.

This study analyzes 255 chronic osteomyelitis patients in northern China, finding higher prevalence in males aged 41-50, common infection sites, and better outcomes with two-stage debridement and antibiotic-loaded PMMA beads.

This study identifies AtERG2, a mitochondrial GTPase in Arabidopsis, as essential for early embryo development, with mutants showing seed abortion and ROS accumulation.

This paper shows tau protein forms liquid droplets with RNA, specifically tRNAs, through complex coacervation, and prolonged droplet residency can lead to beta-sheet formation and aggregation.