Author

S. K. Sahu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Immunology· 2 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Assay:DNA methylation· 2

Frequent Co-Authors

H. Liu· 3 shared H. S. Kulkarni· 2 shared J. McPhatter· 2 shared J. P. Atkinson· 2 shared L. Ma· 2 shared L. Zhu· 2 shared X. Liu· 2 shared X. Wu· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersMicrobiology

H. Liu

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Author profile →

9 papers

Recent·Most cited

In Silico Characterization of Intracellular Localization Signals and Structural Features of Mosquito Densovirus (MDV) Viral Proteins

T. K. Barik, S. N. Swain, S. K. Sahu, U. R. Acharya, H. C. Metz, J. L. Rasgon

This study identifies putative nuclear localization and export signals in mosquito densovirus proteins using in silico analysis, enhancing understanding of viral protein trafficking and potential applications in mosquito control.

bioRxiv · Dec 13, 2023 · PreprintMicrobiology

A Unified Catalog of 19,251 Non-human Reference Species Genomes Provides New Insights into the Mammalian Gut Microbiomes

X. Li, C. Tian, D. Zhuang, L. Tian, X. Shi, L. Bai, H. Gao, H. Zhou, F. Zhao, M. Dai, L. Zhu, Q. Wu, X. Liu, T. Zhang, J. Sang, , Z. Zhang

The paper catalogs 19,251 non-human reference genomes from Qinghai-Tibetan Plateau animals, revealing new insights into mammalian gut microbiome diversity and host-microbe interactions.

bioRxiv · May 16, 2022 · PreprintMicrobiology

Lung epithelial cell-derived C3 protects against pneumonia-induced lung injury

A. N. Ozanturk, S. K. Sahu, D. H. Kulkarni, L. Ma, R. A. Barve, J. McPhatter, L. Garnica, L. Dannull, X. Wu, S. L. Brody, J. P. Atkinson, H. S. Kulkarni

The paper shows lung-derived C3 reduces pneumonia-induced lung injury through the Factor B pathway, independent of circulating C3 levels.

bioRxiv · Feb 3, 2022Immunology

MYC regulates a pan-cancer network of co-expressed oncogenic splicing factors

L. Urbanski, M. Brugiolo, S. Park, B. L. Angarola, N. K. Leclair, P. Palmer, S. K. Sahu, O. Anczukow

The paper identifies a pan-cancer splicing factor module regulated by MYC, showing its role in splicing changes and tumor progression across multiple cancer types.

bioRxiv · Nov 24, 2021Cancer Biology

Increased complement activation is a distinctive feature of severe SARS-CoV-2 infection.

L. Ma, S. K. Sahu, M. Cano, V. Kuppuswamy, J. Bajwa, J. McPhatter, A. B. Pine, M. M. Meizlish, G. Goshua, C. H. Chang, H. Zhang, C. Price, P. Bahel, H. M. Rinder, T. Lei, , H. S. Kulkarni

The paper shows that complement activation is higher in severe SARS-CoV-2 infection compared to influenza and non-COVID respiratory failure, with the alternative pathway linked to worse outcomes.

bioRxiv · Feb 22, 2021Immunology

Modeling Protein Association from Homogeneous to Mixed Environments: A Reaction-Diffusion Dynamics Approach

M. Biswas, S. K. Sahu

The paper models protein association in crowded environments with varying crowder properties and finds size is more influential than shape in stabilization.

bioRxiv · Jan 25, 2021Biophysics

Deficient uracil base excision repair leads to persistent dUMP in HIV proviruses during infection of monocytes and macrophages

M. Meshesha, A. Esadze, J. Cui, N. Churgulia, S. K. Sahu, J. T. Stivers

This study shows that monocytes lack functional uracil base excision repair, leading to persistent dUMP in HIV proviruses, while macrophages have limited hUNG2 activity, affecting viral infectivity and diversification.

PLOS ONE · Jul 14, 2020Peer-reviewedMicrobiology

Single-cell screening of SARS-CoV-2 target cells in pets, livestock, poultry and wildlife

D. Chen, J. Sun, J. Zhu, X. Ding, T. Lan, L. Zhu, R. Xiang, P. Ding, H. Wang, X. Wang, W. Wu, J. Qiu, S. Wang, H. Li, F. An, , X. Xu

The paper screens SARS-CoV-2 target cells across 11 animal species using single-cell transcriptomes, finding higher proportions in cats and detecting them in multiple pig cell types.

bioRxiv · Jun 13, 2020 · PreprintCell Biology

Comparative analyses of 3654 chloroplast genomes unraveled new insights into the evolutionary mechanism of green plants

W. Mu, T. Yang, X. Liao, Y. Liu, S. K. Sahu, X. Liu, H. Liu, M. L. Strube, B. Zhong, L. Yang

The paper compares 3654 chloroplast genomes to uncover evolutionary patterns in green plants, identifying gene clusters and IR expansions.

bioRxiv · Jun 3, 2019 · PreprintPlant Biology