Author

Y. Imai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Kumar· 1 shared A. Laurent· 1 shared A. Nishimura· 1 shared A. Satsuka· 1 shared A. W. Norris· 1 shared B. de Massy· 1 shared C. A. Kulkarni· 1 shared C. Kang· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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1 shared paperPhysiology

A. Kumar

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

PRDM9 drives the location and rapid evolution of recombination hotspots in salmonids

M. Raynaud, P. Sanna, J. Joseph, J. Clement, Y. Imai, J.-J. Lareyre, A. Laurent, N. Galtier, F. Baudat, L. Duret, P.-A. Gagnaire, B. de Massy

This study identifies PRDM9's role in driving recombination hotspots in salmonids, showing rapid evolution and conservation of its function across vertebrates.

bioRxiv · Mar 6, 2024 · PreprintEvolutionary Biology

Position-dependent changes in phycobilisome abundance in multicellular cyanobacterial filaments revealed by Raman spectral analysis

J.-i. Ishihara, Y. Imai

The paper uses Raman spectral analysis to show that phycobilisome abundance in Anabaena sp. PCC 7120 varies with position in filaments, with lower levels in vegetative cells distant from heterocysts.

bioRxiv · Feb 14, 2023 · PreprintMicrobiology

Small molecule SWELL1-LRRC8 complex induction improves glycemic control and nonalcoholic fatty liver disease in murine Type 2 diabetes

S. K. Gunasekar, L. Xie, P. R. Chheda, C. Kang, D. M. Kern, C. My-Ta, A. Kumar, J. M. Maurer, E. E. Gerber, W. J. Grzesik, M. Elliot-Hudson, Y. Zhang, C. A. Kulkarni, I. Samuel, J. K. Smith, , R. Sah

This study identifies small molecule modulators of the SWELL1-LRRC8 complex that improve glycemic control and prevent NAFLD in murine T2D by restoring insulin signaling and secretion.

Nature Communications · Feb 10, 2022Peer-reviewedPhysiology

Clomipramine suppresses ACE2-mediated SARS-CoV-2 entry

Y. Kato, S. Yamada, K. Nishiyama, A. Satsuka, S. Re, D. Tomokiyo, J. M. Lee, T. Tanaka, A. Nishimura, K. Yonemitsu, H. Asakura, Y. Ibuki, Y. Imai, N. Kamiya, K. Mizuguchi, , M. Nishida

This study shows clomipramine inhibits SARS-CoV-2 entry into cardiomyocytes and synergizes with remdesivir to suppress infection.

bioRxiv · Mar 13, 2021 · PreprintPharmacology & Toxicology