S. Robinson

Novel Exploration Growth Quantifies Anxiety-like Behaviour in the Elevated Plus Maze

This paper introduces a new measure, novel exploration growth, to quantify anxiety-like behaviour in the elevated plus maze by capturing both exploration and avoidance in a single time series.

Pectin methylesterification modulates cell wall properties to promote neighbour proximity-induced hypocotyl growth

The study shows that pectin methylesterification modulates cell wall properties to enable neighbor proximity-induced hypocotyl growth in Arabidopsis.

Drug screening linked to molecular profiling identifies novel dependencies in patient-derived primary cultures of paediatric high grade glioma and DIPG

The allosteric modulation of Complement C5 by knob domain peptides

This study shows that knob domain peptides modulate complement C5 through allosteric mechanisms, revealing new therapeutic inhibitors and introducing knob domains as low molecular weight antibody fragments.

Genomic asymmetry of the Brassica napus seed: Epigenetic contributions of DNA methylation and small RNAs to subgenome bias

The paper investigates epigenetic regulation in Brassica napus seeds, finding asymmetrical DNA methylation and small RNA patterns favoring the Cn subgenome.

Gene expression profiling reveals subgenome dominance during Brassica napus seed development

The paper uses RNA sequencing and laser microdissection to study subgenome bias in Brassica napus seed development, revealing distinct transcriptional networks and regulatory roles for the An and Cn subgenomes.

Lipid metabolism links nutrient-exercise timing to insulin sensitivity in men classified as overweight or obese.

This study shows that exercising before nutrient intake increases lipid utilization and improves insulin sensitivity in overweight or obese men over 6 weeks.

A novel bioreactor technology for modelling fibrosis in human and rodent precision-cut liver slices.

This paper develops a bioreactor system that extends the viability of precision-cut liver slices (PCLS) to 6 days under normoxic conditions and demonstrates its use in modeling fibrogenesis and testing anti-fibrotic drugs.

Transcriptome dynamics at the Arabidopsis graft junction reveal an inter-tissue recognition mechanism that activates vascular regeneration

The paper studies gene expression changes in grafted Arabidopsis hypocotyls to identify a recognition mechanism that activates vascular regeneration.

An automated confocal micro-extensometer enables in vivo quantification of mechanical properties with cellular resolution.

The paper introduces an automated confocal micro-extensometer (ACME) to measure mechanical properties in live plant tissue with cellular resolution, demonstrating its use in studying gibberellic acid-induced mechanical gradients in Arabidopsis hypocotyls.