Author

S. Syal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Organism:Arabidopsis· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

E. Geisinger· 4 shared R. R. Isberg· 4 shared T. van Opijnen· 3 shared A. Farinha· 2 shared D. W. Lazinski· 2 shared G. Vargas-Cuebas· 2 shared J. Anthony· 2 shared J. Bai· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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4 shared papersMicrobiology

E. Geisinger

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Identification of Determinants that Allow Maintenance of High-Level Fluoroquinolone Resistance in Acinetobacter baumannii

E. Hamami, W. Huo, A. Castaneda, J. Bai, S. Syal, J. C. Ortiz-Marquez, T. van Opijnen, E. Geisinger, R. R. Isberg

The paper identifies proteins essential for maintaining fitness in Acinetobacter baumannii strains overexpressing RND efflux pumps, highlighting the role of outer membrane integrity and compensatory mechanisms.

bioRxiv · Oct 3, 2023 · PreprintMicrobiology

Essential gene analysis in Acinetobacter baumannii by high-density transposon mutagenesis and CRISPR interference

J. Bai, Y. Dai, A. Farinha, A. Y. Tang, S. Syal, G. Vargas-Cuebas, D. Surujon, R. R. Isberg, T. van Opijnen, E. Geisinger

This study identifies essential genes in Acinetobacter baumannii using transposon mutagenesis and a CRISPRi system, revealing new factors and conditionally essential processes.

bioRxiv · Sep 15, 2020Microbiology

Antibiotic hypersensitivity signatures identify targets for attack in the Acinetobacter baumannii cell envelope

E. Geisinger, N. J. Mortman, Y. Dai, M. Cokol, S. Syal, A. Farinha, D. Fisher, A. Tang, D. W. Lazinski, S. Wood, J. Anthony, T. Opijnen, R. R. Isberg

This study identifies antibiotic hypersensitivity signatures in A. baumannii to discover new targets for attacking the pathogen's cell envelope.

bioRxiv · Mar 11, 2020Microbiology

The landscape of intrinsic and evolved fluoroquinolone resistance in Acinetobacter baumannii includes suppression of drug-induced prophage replication

E. Geisinger, G. Vargas-Cuebas, N. J. Mortman, S. Syal, E. Wainwright, D. W. Lazinski, S. Wood, Z. Zhu, J. Anthony, T. van Opijnen, R. R. Isberg

This paper identifies mutations that alter fluoroquinolone sensitivity in Acinetobacter baumannii and shows that preferential Topo IV poisoning leads to prophage induction and SOS response activation.

bioRxiv · Oct 14, 2018 · PreprintMicrobiology