Author

S. Vorobiev

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:cryo-EM· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

G. T. Montelione· 2 shared J. F. Hunt· 2 shared A. Gagarinova· 1 shared A. Hosseinnia· 1 shared A. Mezzell· 1 shared B. J. Loughlin· 1 shared B. Schweibenz· 1 shared B. Shurina· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersBiochemistry

G. T. Montelione

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The NS1 protein of influenza B virus binds 5'-triphosphorylated dsRNA to suppress RIG-I activation and the antiviral innate immune response

R. Woltz, B. Schweibenz, S. E. Tsutakawa, C. Zhao, L.-C. Ma, B. Shurina, G. L. Hura, R. John, S. Vorobiev, S. Gurla, M. Solotchi, J. A. Tainer, R. M. Krug, S. S. Patel, G. T. Montelione

bioRxiv · Sep 25, 2023 · PreprintBiochemistry

Mechanism of dual pharmacological correction and potentiation of human CFTR

C. Wang, Z. Yang, B. J. Loughlin, H. Xu, G. Veit, S. Vorobiev, O. B. Clarke, F. Jiang, Y. Li, S. Singh, Z. Rich, E. R. Menten, R. A. Grassucci, W. Wang, A. Mezzell, , J. F. Hunt

This paper uses cryo-EM to reveal how VX445 corrects CFTR folding and gating defects by altering allosteric communication pathways.

bioRxiv · Oct 10, 2022 · PreprintBiophysics

YhcB (DUF1043), a novel cell division protein conserved across gamma-proteobacteria

J. Mehla, G. Liechti, R. M. Morgenstern, J. H. Caufield, A. Hosseinnia, A. Gagarinova, S. Phanse, M. Brockett, N. Sakhawalkar, M. Babu, R. Xiao, G. T. Montelione, S. Vorobiev, T. den Blaauwen, J. F. Hunt, P. Uetz

This study characterizes YhcB, a conserved gamma-proteobacterial protein, showing it is essential for cell division and envelope integrity through genetic, structural, and interaction analyses.

bioRxiv · Dec 31, 2020Microbiology