The HLA-II immunopeptidome of SARS-CoV-2
S. Weingarten-Gabbay, D.-Y. Chen, S. Sarkizova, H. B. Taylor, M. Gentili, L. R. Pearlman, M. R. Bauer, C. M. Rice, K. R. Clauser, N. Hacohen, S. A. Carr, J. G. Abelin, M. Saeed, P. C. Sabeti
The paper identifies SARS-CoV-2 peptides presented by HLA-II complexes, showing their association with CD4+ T cell epitopes and distinct targeting of viral proteins compared to HLA-I.
bioRxiv · May 26, 2023Microbiology