Author

Keith R. Reddig

University of Massachusetts Chan Medical School

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Chloe DiMarzio· 2 shared Gregory M. Hendricks· 2 shared Mark KellyiD· 2 shared Michael CzechiD· 2 shared Adı́lson GuilhermeiD· 1 shared Anand DesaiiD· 1 shared Anastasia KhvorovaiD· 1 shared Andre F. C. VieiraiD· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Chloe DiMarzio

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Seipin mediates Perilipin-1 recruitment to lipid droplets to preserve human adipocyte identity

Denise Zhong, Ioanna Stavrakaki, Anand Desai, Tiffany DeSouza, Sabine Linskey, Shannon Joyce, Courtney L. Hatton, Danna Garcia, Reyan Kassam, Gregory M. Hendricks, Keith R. Reddig, Guangping Gao, Jun Xie, Maria Paz Gonzalez-Perez, Andre F. C. Vieira, , Silvia Corvera

This study shows seipin is essential for recruiting Perilipin-1 to lipid droplets in human adipocytes, maintaining adipocyte identity and preventing de-differentiation.

bioRxiv · Nov 9, 2025 · PreprintCell Biology

Dual targeting of hepatocyte DGAT2 and stellate cell FASN alleviates nonalcoholic steatohepatitis in mice.

Batuhan Yenilmez, Shauna M. Harney, Chloe DiMarzio, Mark Kelly, Kyounghee Min, Dimas Echeverria, Brianna M. Bramato, Samuel O. Jackson, Keith R. Reddig, Jason K. Kim, Anastasia Khvorova, Michael Czech

This study shows that targeting both DGAT2 in hepatocytes and FASN in stellate cells reduces NASH in mice more effectively than targeting either gene alone.

bioRxiv · Jul 5, 2023 · PreprintMolecular Biology

De novo lipogenesis fuels adipocyte autophagosome membrane dynamics

Leslie A. Rowland, Adı́lson Guilherme, Felipe dos Santos Henriques, Chloe DiMarzio, Nicole Wetoska, Mark Kelly, Keith R. Reddig, Gregory M. Hendricks, Meixia Pan, Xianlin Han, Olga Ilkayeva, Christopher B. Newgard, Michael Czech

This study identifies de novo lipogenesis as a critical source of fatty acids for autophagosome membrane dynamics in adipocytes, showing that Fasn deficiency impairs autophagy and p62 degradation.

bioRxiv · May 25, 2022 · PreprintMolecular Biology