Author

Sarai M. Williams

Pacific Northwest National Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Systems Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:proteomics· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:metabolomics· 1

Frequent Co-Authors

Ernesto Satoshi NakayasuiD· 2 shared Aizhong Fu· 1 shared Alan J. WolfeiD· 1 shared Athena A Shepmoes· 1 shared Brandon Lewis· 1 shared Brooke L. Deatherage KaiseriD· 1 shared Camille Krieger· 1 shared Carsten SchultziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSystems Biology

Ernesto Satoshi NakayasuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

PTMOverlay: A Proteomic Tool to Visualize Post-Translational Modifications Across Evolution

Camille Krieger, Zachary Joseph Everton, Youngki You, Brandon Lewis, Thomas Bank, Meagan Burnet, Sarai M. Williams, Hanna E. Walukiewicz, Christopher V. Rao, Alan J. Wolfe, Samuel Harris Payne, Ernesto Satoshi Nakayasu

PTMOverlay visualizes post-translational modifications across species by aligning PTM sites to protein sequences, revealing conserved modifications in bacterial central carbon metabolism.

bioRxiv · Feb 6, 2026 · PreprintSystems Biology

Single-Islet Proteomics Maps Pseudo-Temporal Islet Immune Responses and Dysfunction in Stage 1 Type 1 Diabetes

Shane S. Kelly, Soumyadeep Sarkar, Sarai M. Williams, Aizhong Fu, Elizabeth Ashley Butterworth, Tyler J. Sagendorf, Lorenz A. Nierves, Yu Mi Kwon, Xiaolu Li, Vladislav Petyuk, Jing Chen, Ernesto Satoshi Nakayasu, Mark A. Atkinson, Rohit Kulkarni, Clayton E. Mathews, , Weijun Qian

The paper uses single-islet proteomics to analyze pseudo-temporal immune responses and beta-cell dysfunction in stage 1 T1D, identifying key pathways involved in islet dysfunction.

bioRxiv · Nov 10, 2025 · PreprintSystems Biology

Multi-Omic Profiling Identifies Conserved Metabolic Pathways Critical for SARS-CoV-2 Variants Infection

Scotland E. Farley, Jennifer E Kyle, Helene Jahn, Lisa Bramer, Paul Piehowski, Athena A Shepmoes, Brooke L. Deatherage Kaiser, Sarai M. Williams, Josie Eder, Carsten Schultz, Fikadu Tafesse

bioRxiv · Jun 2, 2025 · PreprintSystems Biology