Author

Sonke Svenson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:clustering· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Organism:non-human primate· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Angela Xinyi Nan· 2 shared Brett EstesiD· 2 shared Jenny XieiD· 2 shared Jonathan D. FinniD· 2 shared Maike Thamsen Dunyak· 2 shared Martin MeagheriD· 2 shared Patrick HannaiD· 2 shared Rejina Pokharel· 2 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Angela Xinyi Nan

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Author profile →

2 papers

Recent·Most cited

Low RT-based Genome Editing Fidelity in Mouse Hepatocytes: Challenges and Solutions

Maike Thamsen Dunyak, Patrick Hanna, Angela Xinyi Nan, Jessica R. Von Stetina, Rejina Pokharel, Mollie O’Hara, Brett Estes, Kangni Zheng, Sonke Svenson, Jason L. Andresen, Wei Li, Mini Agrawal, Chase Hughes, Makayla Spicer, Vimal Choudhary, , Jonathan D. Finn

The paper identifies low fidelity in RT-based genome editing in non-dividing mouse hepatocytes and proposes solutions using neonatal mice and transgenic models.

bioRxiv · Oct 31, 2024 · PreprintBioengineering

Curative levels of endogenous gene replacement achieved in non-human primate liver using programmable genomic integration

Jenny Xie, Maike Thamsen Dunyak, Patrick Hanna, Angela Xinyi Nan, Brett Estes, Jesse C. Cochrane, Shuai Wu, Jie Wang, Connor McGinnis, Qiang Wang, Rejina Pokharel, Dev Paudel, Jason Zhang, Dan Li, Parth H. Amin, , Jonathan D. Finn

This paper demonstrates programmable genomic integration in non-human primate liver, achieving curative levels of gene expression in over 50% of liver cells.

bioRxiv · Oct 12, 2024 · PreprintBioengineering