Author

T. Hirata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Evolutionary Biology· 1 Immunology· 1 Scientific Communication & Education· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

T. Kinoshita· 2 shared Y. Murakami· 2 shared A. Hoellein· 1 shared A. Knaus· 1 shared A. Nakazawa· 1 shared A. Ninomiya· 1 shared B. Hoechsmann· 1 shared D. Yoshinaga· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

T. Kinoshita

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

HOIL-1L deficiency induces cell cycle alteration which causes immaturity of myocyte and fibrogenesis

K. Akagi, S. Baba, H. Fujita, Y. Fuseya, D. Yoshinaga, H. Kubota, E. Kume, F. Fukumura, K. Matsuda, T. Tanaka, T. Hirata, K. Iwai, J. Takita

This study shows HOIL-1L deficiency leads to cell cycle defects and fibrosis in myotubes and cardiomyocytes, contributing to myopathy and dilated cardiomyopathy.

bioRxiv · Sep 29, 2023 · PreprintCell Biology

Cross-talks of glycosylphosphatidylinositol biosynthesis with glycosphingolipid biosynthesis and ER-associated degradation

Y. Wang, Y. Maeda, Y. Liu, Y. Takada, A. Ninomiya, T. Hirata, M. Fujita, Y. Murakami, T. Kinoshita

The paper identifies B3GALT4's dual role in GPI and glycosphingolipid biosynthesis and shows ER-associated degradation suppresses GPI biosynthesis when GPI transfer to proteins is defective.

bioRxiv · Aug 24, 2019Cell Biology

Complement- and inflammasome-mediated autoinflammation-paroxysmal nocturnal hemoglobinuria

B. Hoechsmann, Y. Murakami, M. Osato, A. Knaus, M. Kawamoto, N. Inoue, T. Hirata, S. Murata, M. Anliker, T. Eggerman, M. Jaeger, R. Floettmann, A. Hoellein, S. Murase, Y. Ueda, , T. Kinoshita

This study identifies AIF-PNH as a disease caused by germline and somatic mutations in PIGT, leading to complement activation and inflammasome-mediated IL-1β secretion, which is treatable with eculizumab.

bioRxiv · May 13, 2019 · PreprintImmunology

Frequent Non-random Shifts in the Temporal Sequence of Developmental Landmark Events during Teleost Evolutionary Diversification

F. Ito, T. Matsumoto, T. Hirata

This study analyzes the evolutionary changes in developmental sequences across 31 teleost species, finding frequent non-random shifts in the timing of developmental landmark events.

bioRxiv · Apr 19, 2019 · PreprintEvolutionary Biology

A survey of public attitudes towards third-party reproduction in Japan in 2014

N. Yamamoto, T. Hirata, G. Izumi, A. Nakazawa, S. Fukuda, K. Neriishi, T. Arakawa, M. Takamura, M. Harada, Y. Hirota, K. Koga, O. Wada-Hiraike, T. Fujii, M. Irahara, Y. Osuga

This study surveys public attitudes towards third-party reproduction and disclosure in Japan, finding that gender, age, and infertility experience influence opinions.

bioRxiv · May 22, 2018Scientific Communication & Education