T. Arakawa

Crystal structure of Bifidobacterium bifidum glycoside hydrolase family 110 α-galactosidase specific for blood group B antigen

The paper presents the crystal structure of a blood group B antigen-specific α-galactosidase and identifies key residues for antigen recognition and protein stability.

Charge neutralization and β-elimination cleavage mechanism of family 42 L-rhamnose-α-1,4-D-glucuronate lyase revealed using neutron crystallography

This paper uses neutron crystallography to reveal the charge neutralization and β-elimination mechanism of FoRham1, an enzyme that cleaves gum arabic.

Efficient Development of Platform Cell Lines Using CRISPR-Cas9 and Transcriptomics Analysis

The paper develops CRISPR-Cas9 mutants of U87MG cells to create platform cell lines for drug testing, finding that transcriptomic analysis helps identify clones with minimal phenotypic divergence from wild type.

Crystallographic and cryogenic electron microscopic structures and enzymatic characterization of sulfur oxygenase reductase from Sulfurisphaera tokodaii

This paper reports the biochemical and structural characterization of SOR from Sulfurisphaera tokodaii, presenting high-resolution crystal and cryo-EM structures and analyzing the role of iron and cysteines in catalysis.

Crystal structure of β-L-arabinobiosidase belonging to glycoside hydrolase family 121

The paper presents the crystal structure of β-L-arabinobiosidase (HypBA2) from Bifidobacterium longum, revealing its catalytic mechanism and conserved residues essential for substrate binding and catalysis.

A survey of public attitudes towards third-party reproduction in Japan in 2014

This study surveys public attitudes towards third-party reproduction and disclosure in Japan, finding that gender, age, and infertility experience influence opinions.