T. Kageyama

Commensal-specific CD4 T cells promote inflammation in the central nervous system via molecular mimicry

This study shows that specific T cells recognizing commensal bacteria can cause CNS inflammation through molecular mimicry of host proteins.

Reprogramming of three-dimensional microenvironments for in vitro hair follicle induction

This paper demonstrates the in vitro induction of hair follicles by reprogramming three-dimensional microenvironments through controlled epithelial-mesenchymal interactions, resulting in the formation of hair follicloids with functional hair shafts.

Effects of source sample amount on biodiversity surveys of bacteria, fungi, and nematodes in soil ecosystems

The paper examines how varying soil sample amounts affect DNA metabarcoding results for bacteria, fungi, and nematodes, finding that lower sample amounts underestimate nematode diversity.

Immunological features that determine the strength of antibody responses to BNT162b2 mRNA vaccine against SARS-CoV-2

The paper identifies immunological features, including B cell frequencies and CD8+ T cell activation, that correlate with antibody response strength to the BNT162b2 mRNA vaccine.

Redundant cytokine requirement for intestinal microbiota-induced Th17 cell differentiation in draining lymph nodes

This study identifies redundant cytokine signals, particularly IL-6, IL-21, and IL-23, that drive Th17 cell differentiation in mesenteric lymph nodes induced by segmented filamentous bacteria.