Author

Tai Ngo

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:imaging· 3 Organism:mouse· 3 Research Focus:spatial domain detection· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Kevin M. DeaniD· 4 shared Hazel M. BorgesiD· 3 shared Qionghua SheniD· 3 shared Hao ZhuiD· 2 shared John HaugiD· 2 shared Reto Paul FiolkaiD· 2 shared Sean J. MorrisoniD· 2 shared Seweryn GałeckiiD· 2 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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4 shared papersBiophysics

Kevin M. DeanORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Leptin Receptor+ cells create a perisinusoidal niche for thrombopoiesis in the bone marrow by synthesizing CXCL14

Yuanyuan Xue, Ruixuan Zhang, Maowu Luo, Amanda R. Reyes, Salma Merchant, Trevor S. Tippetts, Gerik Grabowski, Tai Ngo, Y. Zhang, Zhiguo Shang, Nisi Jiang, Nathaniel S. Tjahjono, Elise C. Jeffery, Yafeng Li, Tao Wei, , Sean J. Morrison

The paper identifies LepR+ cells as a niche for thrombopoiesis by producing CXCL14, which regulates lipid metabolism and terminal differentiation in megakaryocytes.

bioRxiv · Oct 5, 2026 · PreprintCell Biology

Deciphering the Multiscale Morphology of Somatic Oncogenic Alterations in Hepatocellular Carcinoma

Qionghua Shen, Tai Ngo, Hanieh Mazloom-Farsibaf, Kelly Wong, Lin Li, Kushal Bhatt, Felix Zhou, Bo-Jui Chang, Xiaoding Wang, Zhiguo Shang, John Haug, Hazel M. Borges, Reto Paul Fiolka, Hao Zhu, Kevin M. Dean

This study maps how distinct oncogenic drivers induce unique multiscale architectural changes in liver tissue, revealing mutation-specific remodeling across cellular and mitochondrial structures.

bioRxiv · Jul 16, 2026 · PreprintCancer Biology

Altair-dvOPM: an open-access platform for large-field three-dimensional tissue imaging

Tai Ngo, Muaaz Faiyazuddin, Trung D. Nguyen, John Haug, Qionghua Shen, Seweryn Gałecki, Hazel M. Borges, Bingying Chen, Xiaoding Wang, Hao Zhu, Samuel S. Pappas, Fabian F. Voigt, Reto Paul Fiolka, Kevin M. Dean

Altair-dvOPM is an open-access microscope for large-field 3D tissue imaging, achieving micrometer resolution without custom objectives or specialized alignment.

bioRxiv · May 12, 2026 · PreprintBiophysics

Feature-Driven Whole-Tissue Imaging with Subcellular Resolution

Jinlong Lin, Zach Marin, Xiaoding Wang, Hazel M. Borges, Qionghua Shen, Pierre-Emmanuel N'Guetta, Xuemei Luo, Baylee A. Porter, Yuanyuan Xue, Md Torikul Islam, Tai Ngo, Doreen Idonije, Seweryn Gałecki, Arin B. Aurora, Hu Zhao, , Kevin M. Dean

The paper introduces MCT-ASLM, a microscopy platform that enables subcellular resolution imaging of whole tissues, demonstrating its application in studying neuronal circuits, kidney innervation, and tumor microenvironments.

Cell Reports Methods · Sep 1, 2025Peer-reviewedBiophysics