Author

Tommy J. Krug

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

David A. WeitziD· 4 shared Nadia A. ErkampiD· 2 shared Robert D. GoldmaniD· 2 shared Tomas ŠneiderisiD· 2 shared Tuomas P. J. KnowlesiD· 2 shared Alexander V. Ludlow· 1 shared Alexandra J. Zhou· 1 shared An‐Qi CheniD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersBiophysics

David A. WeitzORCID

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Author profile →

4 papers

Recent·Most cited

FilaBuster: A Strategy for Rapid, Specific, and Spatiotemporally Controlled Intermediate Filament Disassembly

Andrew S. Moore, Tommy J. Krug, Simon B. Hansen, Alexander V. Ludlow, Jonathan B. Grimm, Anthony X. Ayala, Sarah E. Plutkis, Nan Wang, Robert D. Goldman, Ohad Medalia, Luke D. Lavis, David A. Weitz, Jennifer Lippincott‐Schwartz

FilaBuster enables rapid, specific, and spatiotemporally controlled disassembly of intermediate filaments in living cells using a three-step photochemical strategy.

bioRxiv · Apr 20, 2025 · PreprintCell Biology

Differential interactions determine anisotropies at interfaces of RNA-based biomolecular condensates

Nadia A. Erkamp, Mina Farag, Yuanxin Qiu, Daoyuan Qian, Tomas Šneideris, Tingting Wu, Timothy J. Welsh, Hannes Ausserwöger, Tommy J. Krug, Gaurav Chauhan, David A. Weitz, Matthew D. Lew, Tuomas P. J. Knowles, Rohit V. Pappu

The paper investigates anisotropies in RNA-based biomolecular condensate interfaces, finding that purine-rich RNAs drive phase separation while pyrimidine-rich RNAs accumulate at interfaces, with distinct motion patterns observed using single-molecule imaging.

Nature Communications · Apr 11, 2025Peer-reviewedBiophysics

Phase separated liquid vimentin droplets stabilize actin fibers through wetting

Arkaprabha Basu, Tommy J. Krug, Benjamin du Pont, Qiaoling Huang, Sijie Sun, Stephen A. Adam, Robert D. Goldman, David A. Weitz

This study shows vimentin forms liquid droplets that stabilize actin fibers by wetting them, and this behavior is observed in both a mutant and wild-type vimentin.

Proceedings of the National Academy of Sciences · Mar 3, 2025Peer-reviewedBiophysics

Dynamically arrested condensate fusion creates complex structures with varying material properties

Nadia A. Erkamp, Ignacio Sanchez‐Burgos, Alexandra J. Zhou, Tommy J. Krug, Seema Qamar, Tomas Šneideris, Ellie Zhang, Kichitaro Nakajima, An‐Qi Chen, Rosana Collepardo‐Guevara, Jan C. M. van Hest, Peter St George‐Hyslop, David A. Weitz, Jorge R. Espinosa, Tuomas P. J. Knowles

This study investigates how the fusion of biomolecular condensates, influenced by ageing and mixing rates, leads to the formation of multiphase structures with distinct material properties.

bioRxiv · Nov 15, 2024 · PreprintBiophysics