Author

V. Mittal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cancer & tumor microenvironment· 2 Research Focus:drug response / drug discovery· 2 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:Hi-C· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

O. Elemento· 2 shared A. Agustinus· 1 shared A. C. Borczuk· 1 shared A. Irizarry· 1 shared A. Sboner· 1 shared B. Bhinder· 1 shared B. Callaghan· 1 shared B. Dameracharla· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

O. Elemento

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel co-culture strategies of tumor organoids with autologous T-cells reveal clinically relevant combinations of immune-checkpoint and targeted therapies

E. Podaza, J. Capuano, M. Al Assaad, H.-h. Kuo, G. Markowitz, A. Irizarry, H. Ravichandran, S. Ackermann, T. Kane, J. Manohar, M. Sigouros, J. Moyer, B. Bhinder, P. Chandra, M. Malbari, , M. L. Martin

The paper develops co-culture strategies of tumor organoids with autologous T-cells to screen immune-checkpoint and targeted therapy combinations.

bioRxiv · Jul 5, 2023 · PreprintImmunology

Epigenetic dysregulation from chromosomal transit in micronuclei

A. Agustinus, R. Raviram, B. Dameracharla, J. Luebeck, S. Stransky, L. Scipioni, R. Myers, M. DiBona, M. Duran, B. Weigelt, S. Yomtoubian, E. Toufektchan, P. Mischel, V. Mittal, S. Shah, , S. F. Bakhoum

This study shows that chromosomal transit through micronuclei causes epigenetic dysregulation in cancer cells, leading to long-term chromatin accessibility abnormalities.

bioRxiv · Jan 12, 2022Cancer Biology

Evolution of immune escape mechanisms in the progression from preinvasive to invasive human lung adenocarcinoma.

N. K. Altorki, A. C. Borczuk, V. Mittal, O. Elemento, T. E. McGraw

This study compares the immune microenvironment of preinvasive and invasive lung adenocarcinoma using multiplex immunofluorescence, finding increasing immunosuppression with disease progression.

bioRxiv · Apr 17, 2020 · PreprintCancer Biology

Unacylated ghrelin and AZP531 suppress the 3D growth of breast cancers

C. C. Au, J. B. Furness, K. Britt, S. Oshchepkova, H. Ladumor, K. Y. Soo, B. Callaghan, C. Gerard, G. Inghirami, V. Mittal, Y. Wang, X.-Y. Huang, J. A. Spector, E. Andreopoulou, P. Zumbo, , K. A. Brown

This study shows unacylated ghrelin and its analog AZP531 inhibit breast cancer growth in 3D cultures and xenografts by suppressing MAPK signaling and inducing apoptosis.

bioRxiv · Jan 22, 2020 · PreprintCancer Biology