Author

B. Moody

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4 Biochemistry· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 7 Research Focus:cell type annotation· 6 Organism:human· 5 Assay:proteomics· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Assay:flow cytometry· 2

Frequent Co-Authors

T.-Y. Cheng· 4 shared I. Van Rhijn· 3 shared S. Suliman· 3 shared A. Jeucken· 2 shared B. Poolman· 2 shared H. R. Sikkema· 2 shared J. Rossjohn· 2 shared J. van't Klooster· 2 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

4 shared papersBiochemistry

T.-Y. Cheng

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Adipocytes regulate fibroblast function, and their loss contributes to fibroblast dysfunction in inflammatory diseases

H. Faust, T.-Y. Cheng, I. Korsunsky, G. F. M. Watts, S. T. Gal-Oz, W. Trim, K. Kongthong, A. H. Jonsson, D. P. Simmons, F. Zhang, R. Padera, S. Chubinskaya, Accelerating Medicines Partnership Program, K. Wei, S. Raychaudhuri, , M. B. Brenner

The paper shows adipocytes regulate fibroblast function through cortisol signaling, and their loss leads to fibroblast dysfunction in inflammatory diseases.

bioRxiv · May 16, 2023Cell Biology

Effects of BCG vaccination on donor unrestricted T cells in humans

A. Gela, M. Murphy, K. Hadley, W. Hanekom, H. Boom, J. Johnson, D. Hoft, S. Joosten, T. Ottenhoff, S. Suliman, B. Moody, D. Lewinsohn, M. Hatherill, C. Seshadri, E. Nemes, T. Scriba

This study examines the effects of BCG vaccination on donor unrestricted T (DURT) cells in humans, finding increased frequencies of certain T cell subsets in infants but no changes in others.

bioRxiv · Apr 29, 2021 · PreprintImmunology

Dual TCR-alpha expression on MAIT cells as a potential confounder of TCR interpretation

S. Suliman, L. Kjer-Nielsen, S. Iwany, K. Lopez, L. Loh, K. Kedzierska, T. A. Ocampo, A. Corbett, J. McCluskey, J. Rossjohn, S. Leon, R. Calderon, L. Lecca, M. B. Murray, B. Moody, I. Van Rhijn

The paper identifies dual TCR-alpha expression on MAIT cells as a confounder in TCR interpretation, showing non-TRAV1-2 TCRs do not bind MR1-5-OP-RU tetramer.

bioRxiv · Mar 25, 2021 · PreprintImmunology

Benzofuran sulfonates and small self-lipid antigens activate type II NKT cells via CD1d

C. F. Almeida, D. Smith, T.-Y. Cheng, C. Harpur, E. Batleska, T. Nguyen, T. Hilmenyuk, C. V. Nguyen-Robertson, S. J. Reddiex, I. Van Rhijn, J. Rossjohn, A. P. Uldrich, B. Moody, S. J. Williams, D. G. Pellicci, D. I. Godfrey

This study identifies benzofuran sulfonates and small self-lipid antigens as activators of type II NKT cells via CD1d, revealing non-lipidic small molecules that trigger CD1d-restricted NKT cell responses.

bioRxiv · Mar 5, 2021Immunology

Heterologous production of 1-tuberculosinyladenosine in Mycobacterium kansasii models pathoevolution towards the transcellular lifestyle of Mycobacterium tuberculosis.

M. Ghanem, J.-Y. Dube, J. Wang, F. McIntosh, D. Houle, P. Domenech, M. B. Reed, S. Raman, J. Buter, A. J. Minnaard, B. Moody, M. A. Behr

This study introduces the M. tuberculosis-specific gene pair into M. kansasii to model pathoevolution, finding that 1-TbAd production enhances early infection but impairs long-term survival.

bioRxiv · Apr 25, 2020Microbiology

Multimodal memory T cell profiling identifies a reduction in a polyfunctional Th17 state associated with tuberculosis progression

A. Nathan, J. I. Beynor, Y. Baglaenko, S. Suliman, K. Ishigaki, S. Asgari, C.-C. Huang, Y. Luo, Z. Zhang, K. Lopez Tamara, J. Jimenez, R. I. Calderon, L. Lecca, I. van Rhijn, B. Moody, , S. Raychaudhuri

The paper uses multimodal single-cell profiling to identify a reduction in a polyfunctional Th17-like memory T cell state associated with tuberculosis progression.

bioRxiv · Apr 23, 2020 · PreprintImmunology

Periprotein lipidomes of Saccharomyces cerevisiae provide a flexible environment for conformational changes of membrane proteins

J. van't Klooster, T.-Y. Cheng, H. R. Sikkema, A. Jeucken, B. Moody, B. Poolman

The paper investigates periprotein lipidomes in yeast membrane microdomains, finding localized lipid differences that suggest a disordered environment for protein function.

bioRxiv · Mar 31, 2020Biochemistry

Periprotein membrane lipidomics and the role of lipids in transporter function in yeast

J. van't Klooster, T.-Y. Cheng, H. R. Sikkema, A. Jeucken, B. Moody, B. Poolman

The paper investigates lipid composition in yeast plasma membrane microdomains and identifies lipid requirements for transporter function.

bioRxiv · Jan 12, 2020 · PreprintBiochemistry