Author

W. J. Rice

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 3 Approach:experimental assay· 3 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:protein structure prediction· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. Cheng· 3 shared B. Carragher· 3 shared C. S. Potter· 3 shared E. T. Eng· 3 shared L. Y. Kim· 3 shared A. J. Noble· 2 shared A. des Georges· 1 shared A. I. Fernandez-Marino· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBiophysics

A. Cheng

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Author profile →

5 papers

Recent·Most cited

Structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators

P. Selvakumar, A. I. Fernandez-Marino, N. Khanra, C. He, A. J. Paquette, B. Wang, R. Huang, V. V. Smider, W. J. Rice, K. J. Swartz, J. R. Meyerson

This study determines the structures of the T cell potassium channel Kv1.3 with immunoglobulin modulators, revealing two distinct mechanisms to suppress channel activity.

bioRxiv · Apr 19, 2022Biophysics

ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection

K. L. Ching, M. de Vries, J. Gago, K. Dancel-Manning, J. Sall, W. J. Rice, C. Barnett, F.-X. Liang, L. E. Thorpe, B. Shopsin, L. N. Segal, M. Dittmann, V. J. Torres, K. Cadwell

The paper identifies ACE2-containing exosomes, termed defensosomes, that inhibit SARS-CoV-2 infection by binding and blocking viral entry.

bioRxiv · Dec 17, 2021Immunology

High Resolution Single Particle Cryo-Electron Microscopy using Beam-Image Shift

A. Cheng, E. T. Eng, L. Alink, W. J. Rice, K. D. Jordan, L. Y. Kim, C. S. Potter, B. Carragher

This study evaluates the impact of beam-image shift on cryo-EM single-particle reconstruction quality by testing different beam tilt angles and analyzing FSC values and water density peaks.

bioRxiv · Apr 26, 2018Biophysics

Routine Determination of Ice Thickness for Cryo-EM Grids

W. J. Rice, A. Cheng, A. J. Noble, E. T. Eng, L. Y. Kim, B. Carragher, C. S. Potter

The paper presents two methods to measure ice thickness in cryo-EM grids during data collection to improve sample preparation and data quality.

bioRxiv · Apr 16, 2018Biophysics

Routine Single Particle CryoEM Sample and Grid Characterization by Tomography

A. J. Noble, V. P. Dandey, H. Wei, J. Brasch, J. Chase, P. Acharya, Y. Z. Tan, Z. Zhang, L. Y. Kim, G. Scapin, M. Rapp, E. T. Eng, W. J. Rice, A. Cheng, C. J. Negro, , B. Carragher

This study uses fiducial-less tomography to analyze cryoEM grids and finds that 90% of particles are adsorbed to air-water interfaces, impacting protein structure and single particle analysis.

bioRxiv · Dec 11, 2017Biophysics