Author

W. Xiang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2 Ecology· 1 Immunology· 1 Microbiology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 2 Approach:microscopy & imaging analysis· 2 Organism:plant (other)· 2 Approach:statistical model· 2

Frequent Co-Authors

X. Wang· 3 shared J. Wang· 2 shared Y. Liu· 2 shared Z. Li· 2 shared A. M. Ellison· 1 shared A. P. Jarman· 1 shared B. Lv· 1 shared C. Liu· 1 shared

Activity by Year

2018-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersMicrobiology

X. Wang

Mutual co-authors in cluster

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8 papers

Recent·Most cited

Omics-assisted systematic exploration of the intricate regulatory network of guvermectin biosynthesis centered by the cluster-situated regulator GvmR in Streptomyces

y. zhang, W. Xiang, S. Li, H. Shi, J. Wang, Z. Dong, C. Liu, X. Wang

The paper identifies GvmR as a key regulator of guvermectin biosynthesis in Streptomyces, revealing its interactions with other regulators and pathways involved in precursor supply and energy synthesis.

bioRxiv · Nov 19, 2023 · PreprintMicrobiology

Biodegradable hyperbranched poly(amine-co-ester)-based polymeric nanoparticles for mRNA delivery

G. Liu, W. Xiang, m. guan, Y. Deng

This study develops a biodegradable hyperbranched poly(amine-co-ester) nanoparticle for efficient and safe mRNA delivery, showing improved performance over existing commercial reagents.

bioRxiv · Jul 20, 2023Bioengineering

The dynamics of protein localisation to restricted zones within Drosophila mechanosensory cilia

W. Xiang, P. zur Lage, F. G. Newton, G. Qiu, A. P. Jarman

The paper investigates the localization dynamics of TRP channels and dynein motor complexes during ciliogenesis in Drosophila mechanosensory cilia, revealing differences in timing and targeting mechanisms.

bioRxiv · Mar 2, 2022Cell Biology

Lyophilized mRNA-lipid nanoparticle vaccines with long-term stability and high antigenicity against SARS-CoV-2

L. Ai, Y. Li, L. Zhou, H. Zhang, W. Yao, J. Han, J. Wu, R. Wang, W. Wang, P. Xu, Z. Li, C. Wei, H. Chen, J. Liang, M. Guo, , Y. Hu

This paper develops lyophilized mRNA-lipid nanoparticle vaccines that maintain stability at room temperature and show high antigenicity against SARS-CoV-2 variants in preclinical and human trials.

bioRxiv · Feb 10, 2022Immunology

Allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv enhance anti-HIV activity in vitro

H. Pan, J. Wang, H. Liang, Z. Jiang, L. Zhao, Y. Wang, X. Yang, Z. Liang, X. Shen, Q. Lin, Y. Liang, J. Yang, P. Lu, Y. Zhu, W. Xiang, , H. Zhu

This study develops allogeneic gene-edited HIV-specific CAR-T cells secreting PD-1 blocking scFv, showing enhanced anti-HIV activity in vitro compared to autologous CAR-T cells.

bioRxiv · Jan 14, 2022 · PreprintBioengineering

Tomato SlBES1.8 influences leaf morphogenesis by mediating gibberellin metabolism and signaling

D. Su, W. Xiang, Q. Liang, L. Wen, Y. Shi, Y. Liu, Z. Xian, Z. Li

This study identifies SlBES1.8 as a tomato transcription factor that promotes leaf simplification by modulating gibberellin metabolism and signaling.

bioRxiv · Dec 10, 2021Plant Biology

Foundation species across a latitudinal gradient in China

X. Qiao, J. Zhang, Y. Xu, X. Mi, M. Cao, W. Ye, G. Jin, Z. Hao, X. Wang, X. Wang, S. Tian, X. Li, W. Xiang, Y. Liu, Y. Shao, , A. M. Ellison

The paper identifies candidate foundation species in Chinese forests across a latitudinal gradient and finds they are more common in temperate zones than in tropical or boreal regions.

bioRxiv · Mar 15, 2020Ecology

Correlative live and super-resolution imaging reveals the dynamic structure of replication domains

W. Xiang, M. J. Roberti, J.-K. Heriche, S. Huet, S. Alexander, J. Ellenberg

The paper uses correlative live and super-resolution microscopy to study replication domain structure and dynamics in higher eukaryotes, finding RDs are 150 nm in size with specific spacing and mechanical coupling.

bioRxiv · Jan 24, 2018Cell Biology