Author

Wendy A. Pitman

Cornell University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 3 Molecular Biology· 1

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Research Focus:differential expression· 4 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:database / resource· 2 Approach:experimental assay· 2 Assay:ChIP-seq· 1

Frequent Co-Authors

Praveen SethupathyiD· 3 shared Bailey C. E. PeckiD· 2 shared Shengli DingiD· 2 shared Adrian J. McNairniD· 1 shared Ajeet Pratap SinghiD· 1 shared Alessandro BonfiniiD· 1 shared Alexander D. FineiD· 1 shared Amanda T. MahiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersGenomics

Praveen SethupathyORCID

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Author profile →

4 papers

Recent·Most cited

Variation in histone configurations correlates with gene expression across nine inbred strains of mice

Anna L. Tyler, Catrina A. Spruce, Romy Kursawe, Annat Haber, Robyn L. Ball, Wendy A. Pitman, Alexander D. Fine, Narayanan Raghupathy, Michael Walker, Vivek M. Philip, Christopher L. Baker, J. Matthew Mahoney, Gary A. Churchill, Jennifer J. Trowbridge, Michael L. Stitzel, , Gregory W. Carter

The paper examines how histone modifications vary across mouse strains and correlates these variations with gene expression, finding strong links between chromatin states and gene expression, but not DNA methylation.

Genome Research · Jun 1, 2023Peer-reviewedGenomics

Single Cell Analysis Reveals Multi-faceted miR-375 Regulation of the Intestinal Crypt

Michael T. Shanahan, Matt Kanke, Ajeet Pratap Singh, Jonathan Villanueva, Adrian J. McNairn, Oyebola O. Oyesola, Alessandro Bonfini, Yu-Han Hung, Breanna J. Sheahan, Jordana C. Bloom, Rebecca L. Cubitt, Ennessa G. Curry, Wendy A. Pitman, Vera D. Rinaldi, Christopher M. Dekaney, , Praveen Sethupathy

This study identifies miR-375 as a key regulator of intestinal crypt homeostasis, showing its role in stem cell proliferation, tuft cell abundance, and resistance to infection and cancer.

bioRxiv · Oct 1, 2020 · PreprintMolecular Biology

Colonic Epithelial miR-31 Associates with the Development of Crohn’s Phenotypes

Benjamin P. Keith, Jasmine Barrow, Takahiko Toyonaga, Nevzat Kazgan, Michelle Hoffner, Neil Shah, Matthew S. Schaner, Elisabeth A. Wolber, Omar K. Trad, Gregory R. Gipson, Wendy A. Pitman, Matthew Kanke, Shruti Saxena, Nicole Chaumont, Timothy S. Sadiq, , Shehzad Z. Sheikh

This study identifies miR-31 as a marker that stratifies Crohn’s disease patients into two subtypes with distinct clinical outcomes.

JCI Insight · Oct 3, 2018Peer-reviewedGenomics

Functional transcriptomics in diverse intestinal epithelial cell types reveals robust gut microbial sensitivity of microRNAs in intestinal stem cells

Bailey C. E. Peck, Amanda T. Mah, Wendy A. Pitman, Shengli Ding, P. Kay Lund, Praveen Sethupathy

The paper shows microbiota regulate miRNA expression in intestinal stem cells more than other cell types, with miR-375 suppression linked to increased stem cell proliferation.

Journal of Biological Chemistry · Jan 4, 2017Peer-reviewedGenomics