Author

Xueying Lin

Mayo Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetics· 4 Developmental Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:zebrafish· 5

Frequent Co-Authors

Xiaolei XuiD· 5 shared Yonghe DingiD· 3 shared Qi QiuiD· 2 shared A Lavin· 1 shared Alexey V. DvornikoviD· 1 shared Baul YooniD· 1 shared Benoît VanhollebekeiD· 1 shared Changwen Zhang· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersGenetics

Xiaolei XuORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The ift140-Deficient Zebrafish: A Model for Renal Cystogenesis and an F0-Based Screen to Identify Genetic Modifiers of Kidney Cysts

Ping Zhu, A Lavin, Yonghe Ding, Xiaolei Xu, Xueying Lin

This study uses zebrafish mutants to identify genetic modifiers of kidney cysts, finding that mtor and ulk1a inhibition can reverse cyst-related abnormalities.

Journal of the American Society of Nephrology · Sep 9, 2025Peer-reviewedGenetics

An mTOR-Tfeb-Fabp7a signaling axis can be harnessed to ameliorate bag3 cardiomyopathy in adult zebrafish

Yonghe Ding, Feixiang Yan, Baul Yoon, Wei Wei, David Mondaca Ruff, Yuji Zhang, Xueying Lin, Xiaolei Xu

The paper identifies an mTOR-Tfeb-Fabp7a signaling pathway that can repair proteostasis defects and cardiac dysfunction in zebrafish BAG3 cardiomyopathy.

bioRxiv · Oct 24, 2024 · PreprintGenetics

A novel missense mutation in the proprotein convertase gene furinb causes hepatic cystogenesis during liver development in zebrafish

Jillian L. Ellis, Kimberley Jane Evason, Changwen Zhang, Makenzie N. Fourman, Jiandong Liu, Nikolay Ninov, Marion Delous, Benoît Vanhollebeke, Ian T. Fiddes, Jessica P. Otis, Yariv J. Houvras, Steven Arthur Farber, Xiaolei Xu, Xueying Lin, Didier Y. R. Stainier, Chunyue Yin

This study identifies a missense mutation in the furinb gene in zebrafish that causes hepatic cysts by disrupting ER homeostasis and mTOR signaling during liver development.

Hepatology Communications · Aug 26, 2022Peer-reviewedDevelopmental Biology

mtor Haploinsufficiency Ameliorates Renal Cyst Formation in Adult Zebrafish tmem67 Mutants

Ping Zhu, Qi Qiu, Peter C. Harris, Xiaolei Xu, Xueying Lin

This paper establishes an adult zebrafish model of PKD using tmem67 mutants, identifies mTOR inhibition as a potential therapy, and reveals ciliary abnormalities as a primary defect.

Journal of the American Society of Nephrology · Feb 11, 2021Peer-reviewedGenetics

Retinoid X receptor alpha is a spatiotemporally-specific therapeutic target for doxorubicin-induced cardiomyopathy in adult zebrafish

Xiao Ma, Yonghe Ding, Hong Zhang, Qi Qiu, Alexey V. Dvornikov, Maengjo Kim, Yong Wang, Matthew R. Lowerison, Joerg Herrmann, Stephen Carl Ekker, Tzung K. Hsiai, Xueying Lin, Xiaolei Xu

This study identifies RXRA as a therapeutic target for doxorubicin-induced cardiomyopathy in zebrafish by showing its endothelial-specific function and response to FDA-approved agonists.

bioRxiv · Dec 8, 2018 · PreprintGenetics