Y. Feng

SIGAR infers germline genome architecture and rearrangements from short germline DNA reads without requiring a germline assembly, validated in ciliates with high accuracy.

This study clones, expresses, and evaluates the in vitro anticancer activity of Lp16-PSP, a protein from Lentinula edodes, showing selective cytotoxicity against HL-60 cells.

This study investigates the diversity anomaly of Heterotropa in insular versus continental regions by analyzing phylogenetic relationships and floral trait evolution.

This study identifies Paxillin's role in promoting ATP-induced activation of P2X7 receptor and NLRP3 inflammasome through complex formation and deubiquitination.

This study compares clinical characteristics and prognosis of second primary non-small cell lung cancer after cervical cancer with first primary non-small cell lung cancer using SEER data.

This paper develops microbial strains for producing renewable fatty acid esters, achieving high yields and economic competitiveness in bioproduction.

This study investigates the co-production of tet(X6) and mcr-1 resistance genes on a single plasmid in E. coli, revealing their independent mechanisms of antibiotic resistance and the implications for antimicrobial resistance spread.

The paper shows dietary glucose promotes Plasmodium infection by expanding a gut bacterium that alkalizes mosquito midgut, enhancing parasite development.

This study isolates and characterizes a coronavirus from Malayan pangolins that is highly similar to 2019-nCoV, suggesting pangolins may act as an intermediate host.

This paper introduces A-Star, a method for detecting rare mutations with high sensitivity and multiplexing capability, achieving detection as low as 0.01% allele frequency.

This study links cellular virological stages in chronic hepatitis B to liver fibrosis progression through spatial and functional analysis of viral and host gene expression.

This study identifies RNF125's role in regulating HDAC2 and PDX1 to influence pancreatic cancer development and patient outcomes.

This paper identifies a stepwise endonuclease activity in PfAgo that enables multiplex gene detection through a platform called RADAR, applied to distinguish human papillomavirus serotypes.

This study determines the structure of an E. coli transcription activation complex and shows that Crl stabilizes σS to activate transcription without DNA contact.

This study shows STING activates the NLRP3 inflammasome by recruiting NLRP3 to the ER and deubiquitinating it, enhancing IL-1β secretion and inflammatory responses.

The paper describes the discovery and characterization of a novel Klebsiella species, Klebsiella huaxiensis, isolated from a human urine sample.

The paper reports the crystal structure of RBBP1's chromo barrel domain and shows it does not bind DNA, contradicting previous reports of DNA-enhanced histone binding.

This study shows that PGE2 promotes neutrophil reverse migration and anti-inflammatory signaling, aiding inflammation resolution in a zebrafish model.

This study characterizes t-Darpp's structure, metal-binding, and phosphorylation by CDK1 and CDK5, revealing its monomeric form and calcium-binding properties.