Author

Y. Rose Citron

University of California, Berkeley

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:cell signaling & trafficking· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Roberto ZoncuiD· 2 shared A J Green· 1 shared Aakriti JainiD· 1 shared Aaron BodanskyiD· 1 shared Akshay Sharathchandra· 1 shared Alex Maya-RomeroiD· 1 shared Alyssa Terry ReddyiD· 1 shared Amandine BerthetiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersCell Biology

Roberto ZoncuORCID

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Author profile →

4 papers

Recent·Most cited

AEGIS reveals epitope- and clone-resolved convergence of CNS B and T cell autoreactivity in ROHHAD

Aaron Bodansky, Vida Ahyong, Monica T. Dayao, James Asaki, ShiLu Vanasupa, Ravi Dandekar, Shini Chen, Joe Sabatino, Sam Klauer, Giselle M. Knudsen, Carlos Lizama Valenzuela, Krista Mccutcheon, Kelsey Zorn, Sukhman Sidhu, David Yu, , Joseph L. DeRisi

AEGIS identifies epitope- and clone-specific autoimmunity in ROHHAD by linking immune repertoires to self-epitopes, revealing convergence on ZSCAN1 epitopes in the CNS.

bioRxiv · May 11, 2026 · PreprintImmunology

Autophagosomes coordinate an AKAP11-dependent regulatory checkpoint that shapes neuronal PKA signaling

Ashley Segura-Roman, Y. Rose Citron, Myungsun Shin, Nicole Sindoni, Alex Maya-Romero, Simon Rapp, Claire Goul, Joseph Douglas Mancias, Roberto Zoncu

This study identifies AKAP11 as a scaffold linking autophagy to PKA signaling, showing its role in phosphorylation regulation and neuronal homeostasis, with implications for schizophrenia and bipolar disorder.

The EMBO Journal · Apr 22, 2025Peer-reviewedCell Biology

Leucine Aminopeptidase LyLAP enables lysosomal degradation of membrane proteins

Aakriti Jain, Isaac P. Heremans, Gilles Rademaker, Tyler C. Detomasi, Peter J. Rohweder, Dashiell Anderson, Justin Zhang, Grace A. Hernandez, Suprit Gupta, Teresa von Linde, Mike Lange, Martina Spacci, Jiayi Luo, Y. Rose Citron, James A. Olzmann, , Roberto Zoncu

The paper identifies LyLAP as a key enzyme for lysosomal degradation of transmembrane proteins, showing its role in maintaining endocytic activity and lysosomal stability in pancreatic cancer.

Science · Mar 27, 2025Peer-reviewedBiochemistry

Hsp70 chaperone blocks α-synuclein oligomer formation via a novel engagement mechanism

Jiahui Tao, Amandine Berthet, Y. Rose Citron, Paraskevi L. Tsiolaki, Robert F. Stanley, Jason E. Gestwicki, David A. Agard, Lisa McConlogue

This study identifies a novel non-canonical mechanism by which Hsp70 blocks α-synuclein oligomer formation, independent of ATP and the typical substrate-binding cleft.

Journal of Biological Chemistry · Jan 1, 2021Peer-reviewedNeuroscience