Author

Yakov Perlov

Dana-Farber Cancer Institute

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Cell Biology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Aybuke Alici-GaripcaniD· 1 shared Ermanno MalagolaiD· 1 shared Guodong Tie· 1 shared Judith KraiczyiD· 1 shared Onur EskiocakiD· 1 shared Pratik Narendra Pratap SinghiD· 1 shared Qiao ZhouiD· 1 shared Ramesh A. ShivdasaniiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Aybuke Alici-GaripcanORCID

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1 paper

Recent·Most cited

Niche-driven phenotypic plasticity and cis-regulatory dynamics of a revised model for intestinal secretory differentiation

Swarnabh Bhattacharya, Guodong Tie, Pratik Narendra Pratap Singh, Ermanno Malagola, Onur Eskiocak, Ruiyang He, Judith Kraiczy, Wei Gu, Yakov Perlov, Aybuke Alici-Garipcan, Semir Beyaz, Timothy Cragin Wang, Qiao Zhou, Ramesh A. Shivdasani

The paper shows that goblet and Paneth cells share similar gene expression and chromatin features, and their phenotypes are influenced by niche signals like BMP, suggesting a single cell type with plasticity.

Cell stem cell · Feb 8, 2025Peer-reviewedCell Biology