Author

Yvonne Petersen

German Cancer Research Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

Johannes BetgeiD· 3 shared Michael BoutrosiD· 3 shared Elke BurgermeisteriD· 2 shared Erica ValentiniiD· 2 shared Julian E. Riedesser· 2 shared Kim E. BoonekampiD· 2 shared Nadine SchulteiD· 2 shared Philipp AlbrechtiD· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Johannes BetgeORCID

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Author profile →

4 papers

Recent·Most cited

WNT-driven immune evasion promotes malignant transformation of BRAF-mutant colorectal cancer

Manuel Mastel, Aitana Guiseris Martinez, Umberto Pozza, Jasmin Meier, Ioannis Chiotakakos, Sandra Jaun, Carolin Artmann, Gabriele Diamante, Nikolaos Georgakopoulos, Philipp Albrecht, Yvonne Petersen, Saskia Reuter, Barbara Schmitt, Michael Günther, Alexandra Thiran, , René Jackstadt

This study shows that WNT signaling enables immune evasion in BRAF-mutant colorectal cancer, promoting tumor progression through changes in T cell phenotypes.

Gastroenterology · Aug 1, 2026Peer-reviewedCancer Biology

Multi-omics, organoid-based modeling reveals an SRC/mTOR-dependent fetal-like stem cell trajectory in colorectal cancer

Theresa Mulholland, Bogac Aybey, Zhenchong Li, Luisa E. Schwarzmüller, Niklas Rindtorff, Lucrezia Tondo, Ping Sui, Ekin Karabati, Philipp Albrecht, Julian E. Riedesser, Yvonne Petersen, Thilo Miersch, Erica Valentini, Elke Burgermeister, Tianzuo Zhan, , Johannes Betge

The paper identifies a fetal-like stem cell trajectory in colorectal cancer using multi-omics and organoid models, linked to poor prognosis and SRC/mTOR dependency.

bioRxiv · Jul 3, 2026 · PreprintCancer Biology

An organoid platform reveals MEK-PARP co-targeting to enhance radiation response in rectal cancer

Qiyun Xiao, Julian E. Riedesser, Theresa Mulholland, Zhenchong Li, Jonas Buchloh, Philipp Albrecht, Xinchen Yang, Moying Li, Nachiyappan Venkatachalam, Olga Skabkina, Anna Klupsch, Emerich Eichhorn, Li Wang, Sebastian Belle, Nadine Schulte, , Johannes Betge

The paper uses a patient-derived rectal cancer organoid platform to identify MEK and PARP inhibitors that synergize with radiation to enhance treatment response in locally advanced rectal cancer.

Cell Reports Medicine · Aug 1, 2025Peer-reviewedCancer Biology

Arnold tongue entrainment reveals dynamicalprinciples of the embryonic segmentation clock

Paul Gerald Layague Sanchez, Victoria Mochulska, Christian Mauffette Denis, Gregor Mönke, Takehito Tomita, Nobuko Tsuchida-Straeten, Yvonne Petersen, Katharina F. Sonnen, Paul François, Alexander Aulehla

The paper uses a coarse-grained theoretical-experimental approach to study the dynamics of the mouse embryonic segmentation clock, revealing its non-linear oscillator characteristics and long-term feedbacks.

eLife · Aug 25, 2022Peer-reviewedDevelopmental Biology