Z. Dai

This paper introduces label-retention expansion microscopy (LR-ExM) to prevent fluorescence signal loss and enable high-efficiency labeling, achieving molecular resolution in visualizing clathrin-coated pits.

This paper extracts and interprets sequence features affecting peptide MHC binding using yeast display data, showing they accurately predict binding and align with structural knowledge.

This study identifies EGFR downregulation as a mechanism by which HPV infection improves prognosis in cervical and head and neck cancers, suggesting EGFR inhibitors could be potential anti-HPV therapies.

The paper develops a machine learning method to optimize peptide binding to class II MHCs by modifying anchor residues, validated through a yeast display assay.

This study examines how wildfire and its legacy through charcoals affect soil microbial communities in boreal forests over a 29-year chronosequence.

The paper shows that Par-3 and dynein mediate polarized endosome movement during asymmetric division, leading to Notch signaling asymmetry in daughter cells.

This study identifies cathepsin B as a protease with unexpected ligase activity, showing it can both cleave and join peptides through a two-step mechanism.

The paper shows that oxidative stress in NSPCs activates the IFN-I response via FOXO3-regulated lamin modifications, preserving their regenerative potential.

This study investigates microbial nitrogen metabolism in chloraminated drinking water reservoirs using metagenomics, revealing key bacterial roles in nitrification and nitrate assimilation.

This paper develops a bio-active scaffold combining HMGB1 and kartogenin to enhance meniscus healing, showing activation of stem cells and promotion of tissue repair in vitro and in vivo.

The paper compares transcriptomic and metabolic profiles of two table grape cultivars with different berry skin colors, identifying differences in flavonoid and primary metabolite composition and gene expression.

This study compares the impact of disinfection and nutrient limitation on drinking water microbiomes, finding that disinfection reduces diversity and selects for microorganisms using decay products.

This study identifies conditions favoring comammox bacteria in wastewater treatment systems and develops a qPCR assay to quantify them.

This study shows that disinfectant residuals in drinking water systems are linked to higher prevalence of antimicrobial resistance genes in nontuberculous mycobacteria.

This study shows that dietary methionine restriction affects one carbon metabolism in humans and produces therapeutic responses in cancer by altering metabolic pathways.

This study uses oligotyping and genome-resolved metagenomics to identify distinct Candidatus Accumulibacter communities in different EBPR configurations, revealing new MAGs and clade-level diversity.

This study investigates how thermodynamics and enzyme activity regulate metabolic fluxes in pathways, showing that control is primarily determined by overall flux rather than individual enzymes or thermodynamics.