Author

Z. Nwosu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Myers· 2 shared C. A. Lyssiotis· 2 shared L. Zhang· 2 shared P. Sajjakulnukit· 2 shared A. Andren· 1 shared B. Chen· 1 shared B. Magnuson· 1 shared B. S. Nelson· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCancer Biology

A. Myers

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ECM1 Attenuates Hepatic Fibrosis by Interfering with Mediators of Latent TGF-β1 Activation

F. Link, Y. Li, J. Zhao, S. Munker, W. Fan, Z. Nwosu, Y. Yao, S. Wang, C. Huang, S. Hammad, R. Liebe, H. Liu, C. Shao, C. Gao, B. Sun, , S. Wang

This study shows ECM1 prevents hepatic fibrosis by inhibiting TGF-β1 activation, with implications for developing safe anti-fibrotic therapies.

bioRxiv · Dec 12, 2023Cell Biology

Therapeutic targeting of differentiation state-dependent metabolic vulnerabilities in DIPG

N. Mbah, A. Myers, C. Chung, J. Thompson, H. Hong, P. Sajjakulnukit, Z. Nwosu, M. Shan, S. Sweha, D. Maydan, B. Chen, L. Zhang, B. Magnuson, Z. Zui, D. Wahl, , C. A. Lyssiotis

This study identifies metabolic vulnerabilities in DIPG subtypes and shows that targeting these vulnerabilities with specific drugs can extend survival in preclinical models.

bioRxiv · Mar 1, 2022 · PreprintCancer Biology

GOT1 Inhibition Primes Pancreatic Cancer for Ferroptosis through the Autophagic Release of Labile Iron

D. M. Kremer, B. S. Nelson, L. Lin, E. Yarosz, C. J. Halbrook, S. A. Kerk, P. Sajjakulnukit, A. Myers, G. Thurston, S. Hou, E. S. Carpenter, A. Andren, Z. Nwosu, N. Cusmano, S. Wisner, , C. A. Lyssiotis

This study shows that inhibiting GOT1 in pancreatic cancer primes cells for ferroptosis by promoting autophagy-mediated release of labile iron.

bioRxiv · Feb 28, 2020 · PreprintCancer Biology