Janou A. Y. Roubroeks

Prediction of Cell States and Key Transcription Factors of the Human Cornea through Integrated Single-Cell Omics Analyses

This paper integrates single-cell RNA-seq data to create a human corneal cell state meta-atlas and develops a machine learning tool to annotate cell states and identify key transcription factors.

Epigenome-wide profiling in the dorsal raphe nucleus highlights cell-type-specific changes in TNXB in Alzheimer's disease

This study identifies cell-type-specific epigenetic changes in TNXB in Alzheimer's disease using bulk and single-cell analyses of the dorsal raphe nucleus.

A meta-analysis of epigenome-wide association studies in Alzheimer's disease highlights novel differentially methylated loci across cortex

This study performs a meta-analysis of DNA methylation data from Alzheimer's disease patients to identify differentially methylated loci across brain regions and cortex.