Author

Simona Ronzoni

European Institute of OncologyORCID 0000-0002-3976-3406Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alessandro CuomoiD· 1 shared Amir HosseiniiD· 1 shared Andrea BasileiD· 1 shared Angela BachiiD· 1 shared Antonello MaiiD· 1 shared Carlo Ribelle Zucca· 1 shared Chiara SorianiiD· 1 shared Elena CeccacciiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

Alessandro CuomoORCID

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2 papers

Recent·Most cited

Cell cycle control of chromatin creates a therapeutic window for epigenetic therapy in tumors

Kourosh Hayatigolkhatmi, Riccardo Valzelli, Elena Ceccacci, Amir Hosseini, Oualid El Menna, Mauro Romanenghi, Isabella Pallavicini, Emanuel Soda, Ornella Ejlli, Emanuela Villa, Paolo Falvo, Pedro Vizán, Enrique Blanco, Sergi Aranda, Roxana Barkhordar, , Saverio Minucci

This paper shows that extending G1 phase in cancer cells creates a therapeutic window for epigenetic drugs, with LSD1 inhibition and CDK4/6 inhibition working synergistically to induce differentiation and improve survival in AML models.

bioRxiv · Sep 6, 2026 · PreprintCancer Biology

Endocytic control of cell-autonomous and non-cell-autonomous functions of p53

Roberta Cacciatore, Andrea Basile, Stefano Freddi, Irene Schiano Lomoriello, Carlo Ribelle Zucca, Giuseppe Ciossani, Luigi Scietti, Alessandro Cuomo, Simona Ronzoni, Simone Pelicci, Mario Faretta, Elena Zaccheroni, Giuliana Pelicci, Vittoria Matafora, Angela Bachi, , Pier Paolo Di Fiore

This study shows that NUMB's Ex3 exon directs it to the plasma membrane, forming a complex with SNX9 that recruits and transports p53 via exosomes, enabling p53-dependent transcriptional activity in recipient cells.

Advanced Science · Jan 30, 2026Peer-reviewedCancer Biology